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<!-----------------title--------------------->
 
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{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 
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<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div>
 
<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div>
<div style="padding:0em; font-size:100%">[[Special:AllPages|52,619]] human long non-coding RNAs inside</div>
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<div style="padding:0em; font-size:100%">[[:Category:Transcripts|106,063]] human long non-coding RNAs inside</div>
  
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*<span class=plainlinks>[[:Category:Genes|Genes]]</span>
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*[[:Category:Transcripts|Transcripts]]
*[[RiceWiki:GeneFamilies|Gene Families]]
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*[[:Category:Genes|Genes]]
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*[[LncRNAWiki:Classification|Classification]]
 
|style="width:18%;|
 
|style="width:18%;|
*[[RiceWiki:Databases|Databases]]
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*[[LncRNAWiki:Featured|Featured LncRNAs]]
*[[Special:ListUsers|Registered Users]]
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*[http://bigd.big.ac.cn/lncbook/disease Disease]
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*[http://bigd.big.ac.cn/lncbook/function Function]
 
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*[[RiceWiki:Templates|Templates]]
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*[[LncRNAWiki:Small_proteins|Small Proteins]]
--->
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*[http://bigd.big.ac.cn/lgc Prediction]
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*[http://bigd.big.ac.cn/lncbook/blast BLAST]
 
|}
 
|}
 
 
<!---------------welcome Box----------------->
 
<!---------------welcome Box----------------->
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
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<div style="background:#f1f1f1; border-bottom:1px solid #c6c6c6; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Introduction</div>
 
<div style="background:#f1f1f1; border-bottom:1px solid #c6c6c6; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Introduction</div>
<div style="padding:0.5em 0.5em;">lncRNAWiki is a wiki-based database for management of human lncRNAs, aiming to harness collective intelligence to collect, edit, and annotate information about human lncRNAs. This database is a publicly editable and open-content platform for community curation of human lncRNAs, bearing the potential to become a comprehensive and up-to-date knowledge base for human lncRNAs.</div>
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<div style="padding:1em 0.5em;">
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{{LncRNAWiki:Summary}}
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<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an important component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
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</div>
 
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
|-
 
|-
<!-----------Data sources------------>
 
|valign="top" style="border:1px solid #93ff93; background-color:transparent; width:40%;"|
 
<div style="background:#deffde; border-bottom:1px solid #93ff93; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Data sources</div>
 
<div style="padding:0.5em 0.5em;">Here we integrate human lncRNA sequences from GENCODE, NONCODE, LNCipedia, and lncRNAdb, and obtain ~53,000 non-redundant lncRNA transcripts.<br />
 
[[File:Data_source.jpg|center|400px]]</div><br />
 
<div style="text-align:center">'''Note: Purple indicates LncRNAdb.'''</div>
 
  
<!-----------------Classification---------------------->
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<!-----------Featured lncRNAs------------>
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://lncrna.big.ac.cn/index.php/LncRNAWiki:Featured Featured lncRNAs]</div>
<div style="background:#deffde; border-bottom:1px solid #93ff93; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div>
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<div style="padding:0.5em 0.5em;">[[File:Featured-2019-3.png|center|500px|link=LncRNAWiki:Featured]]</div>
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|style="padding:0px 4px;"|
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<!-----------Top 10 lncRNA-associated diseases------------>
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [http://bigd.big.ac.cn/lncbook/disease lncRNA-associated diseases]</div>
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<div style="padding:0.5em 0.5em;">
 
<div style="padding:0.5em 0.5em;">
We previously summarized classification methods of lncRNAs according to their four major features (namely, genomic location and context, effect exerted on DNA sequences, mechanism of functioning, and their targeting mechanism), explored potential relationships between different classification categories, and generalized and compared biological features of different lncRNAs within each category (Ma etal. 2013, RNA Biology). <br />
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''Diseases and their associated lncRNAs' counts are listed below.''
Here, we classify these lncRNAs into 9 groups based on their genomic location. <br />
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[[File:Classfication.jpg|center|400px]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Neoplasms Neoplasms]: 1,077
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Digestive%20System%20Diseases Digestive System Diseases]: 427
 +
 
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Male%20Urogenital%20Diseases Male Urogenital Diseases]: 117
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Female%20Urogenital%20Diseases%20and%20Pregnancy%20Complications Female Urogenital Diseases and Pregnancy Complications]: 196
 +
 
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Respiratory%20Tract%20Diseases Respiratory Tract Diseases]: 224
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Skin%20and%20Connective%20Tissue%20Diseases Skin and Connective Tissue Diseases]: 165
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Endocrine%20System%20Diseases Endocrine System Diseases]: 129
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Cardiovascular%20Diseases Cardiovascular Diseases]: 155
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Congenital,%20Hereditary,%20and%20Neonatal%20Diseases%20and%20Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities]: 150
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Nervous%20System%20Diseases Nervous System Diseases]: 103
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</div>
 
</div>
 
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<!--------------main part two---------------->
 
<!--------------main part two---------------->
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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|-
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<!-----------------Extensively curated---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
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{|style="width:100%;"
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Extensively curated</div>
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|style="width:33%;|
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* [[NONHSAT028508|''HOTAIR'']]
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* [[ENST00000534336.1|''MALAT-1'']]
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* [[NONHSAT017465|''H19'']]
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* [[NONHSAT039745|''MEG3'']]
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* [[ENST00000501122.2|''NEAT1'']]
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* [[ENST00000513868.2|''PVT1'']]
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* [[NONHSAT007663|''GAS5'']]
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* [[Lnc-C9orf53-2:1|''CDKN2B-AS1'']]
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* [[NONHSAT119717|''HOTTIP'']]
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* [[NONHSAT113149|''7SK'']]
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|style="width:33%;|
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* [[BANCR|''BANCR'']]
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* [[BTG3-AS1|''BTG3-AS1'']]
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* [[CERNA2|''CERNA2'']]
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* [[FLICR|''FLICR'']]
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* [[GUARDIN|''GUARDIN'']]
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* [[LINC-ROR|''LINC-ROR'']]
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* [[PINCR|''PINCR'']]
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* [[PLUT|''PLUT'']]
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* [[LUNAR1|''LUNAR1'']]
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* [[Lnc-SRA1-1:1|''SRA'']]
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|style="width:34%;|
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* [[NONHSAT017524|''KCNQ1OT1'']]
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* [[NONHSAT076153|''PCGEM1'']]
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* [[NONHSAT137541|''XIST'']]
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* [[Lnc-EPCAM-1:2|''BCYRN1'']]
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* [[NONHSAT084827|''TUG1'']]
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* [[Lnc-OR10H5-1:1|''UCA1'']]
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* [[NONHSAT107640|''HULC'']]
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* [[NONHSAT129019|''PRNCR1'']]
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* [[TP53COR1|''TP53COR1'']]
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* [[Lnc-CDKN1A-1:1|''PANDAR'']]
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|}
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<!-----------------Function---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://bigd.big.ac.cn/lncbook/function Function]</div>
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<div style="padding:0.5em 0.5em;">
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''Functional mechanisms and their associated lncRNAs' counts are listed below.''
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=transcriptional%20regulation Transcriptional regulation]: 282
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=ceRNA ceRNA]: 73
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=translational%20control Translational control]: 13
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=protein%20localization Protein localization]: 6
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=splicing%20regulation Splicing regulation]: 4
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</div>
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|}
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<!--------------main part three---------------->
 
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
<!------------- Participating---------------->
 
<!------------- Participating---------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent; width:75%"|
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Publications</div>
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">How to Cite</div>
 
<div style="padding:0.5em 1em;">
 
<div style="padding:0.5em 1em;">
* [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 On the classification of long non-coding RNAs.] (2013) ''RNA Biology'', 10(6),1-10.
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If you use any data or information in your work, please cite the following publications.
</div>
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Primary publication:
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* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
  
<!-------------Lab Information-------------->
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Related publication:
|style="padding:0px 4px;"|
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* [https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpbi.82 '''Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook'''.] '' Curr Protoc Bioinformatics 2019''.
|valign="top" style="border:1px solid #66B3FF; background-color:transparent; width:33%"|
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">About Us</div>
 
<div style="padding:0.5em 1em;">Our group works in the field of [http://cbb.big.ac.cn Computational Biology and Bioinformatics] (CBB), currently with a particular focus on building biological knowledge wikis in aid of community curation of massive biological knowledge.
 
 
</div>
 
</div>
  

Latest revision as of 08:01, 16 September 2019



Welcome to LncRNAWiki
106,063 human long non-coding RNAs inside
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

LncRNAWiki, an important component of LncBook, provides community annotations of human lncRNAs
Featured-2019-3.png
Extensively curated

Functional mechanisms and their associated lncRNAs' counts are listed below.

How to Cite

If you use any data or information in your work, please cite the following publications.

Primary publication:

Related publication:

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