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<!-----------------title--------------------->
 
<!-----------------title--------------------->
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 
|style="width:50%; text-align:center; white-space:nowrap; color:#000"|
 
|style="width:50%; text-align:center; white-space:nowrap; color:#000"|
 
<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div>
 
<div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div>
<div style="padding:0em; font-size:100%">[http://bigd.big.ac.cn/lncbook/lncrnas 290,405] human long non-coding RNAs inside</div>
+
<div style="padding:0em; font-size:100%">[[:Category:Transcripts|106,063]] human long non-coding RNAs inside</div>
  
 
|style="width:18%;|
 
|style="width:18%;|
*[http://bigd.big.ac.cn/lncbook/lncrnas Transcripts]
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*[[:Category:Transcripts|Transcripts]]
*[http://bigd.big.ac.cn/lncbook/featuredlncrna Featured LncRNAs]
+
*[[:Category:Genes|Genes]]
 +
*[[LncRNAWiki:Classification|Classification]]
 
|style="width:18%;|
 
|style="width:18%;|
*[http://bigd.big.ac.cn/lncbook/diseases Disease]
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*[[LncRNAWiki:Featured|Featured LncRNAs]]
 +
*[http://bigd.big.ac.cn/lncbook/disease Disease]
 
*[http://bigd.big.ac.cn/lncbook/function Function]
 
*[http://bigd.big.ac.cn/lncbook/function Function]
 
|style="width:18%;|
 
|style="width:18%;|
 +
*[[LncRNAWiki:Small_proteins|Small Proteins]]
 
*[http://bigd.big.ac.cn/lgc Prediction]
 
*[http://bigd.big.ac.cn/lgc Prediction]
 
*[http://bigd.big.ac.cn/lncbook/blast BLAST]
 
*[http://bigd.big.ac.cn/lncbook/blast BLAST]
 
|}
 
|}
 
 
<!---------------welcome Box----------------->
 
<!---------------welcome Box----------------->
 
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<div style="padding:1em 0.5em;">
 
<div style="padding:1em 0.5em;">
 
{{LncRNAWiki:Summary}}
 
{{LncRNAWiki:Summary}}
<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an import component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
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<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an important component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
 
</div>
 
</div>
 
|}
 
|}
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<!-----------Featured lncRNAs------------>
 
<!-----------Featured lncRNAs------------>
 
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
 
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Featured|Featured lncRNAs]]</div>
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://lncrna.big.ac.cn/index.php/LncRNAWiki:Featured Featured lncRNAs]</div>
 +
<div style="padding:0.5em 0.5em;">[[File:Featured-2019-3.png|center|500px|link=LncRNAWiki:Featured]]</div>
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 +
|style="padding:0px 4px;"|
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 +
<!-----------Top 10 lncRNA-associated diseases------------>
 +
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [http://bigd.big.ac.cn/lncbook/disease lncRNA-associated diseases]</div>
 +
 
 
<div style="padding:0.5em 0.5em;">
 
<div style="padding:0.5em 0.5em;">
<table>
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''Diseases and their associated lncRNAs' counts are listed below.''
<tr>
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<td>[[File:Featured-2018.png|left|430px|link=LncRNAWiki:Featured]]</td>
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Neoplasms Neoplasms]: 1,077
<td valign="top">
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Extensively curated:
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Digestive%20System%20Diseases Digestive System Diseases]: 427
 +
 
 +
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Male%20Urogenital%20Diseases Male Urogenital Diseases]: 117
 +
 
 +
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Female%20Urogenital%20Diseases%20and%20Pregnancy%20Complications Female Urogenital Diseases and Pregnancy Complications]: 196
 +
 
 +
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Respiratory%20Tract%20Diseases Respiratory Tract Diseases]: 224
 +
 
 +
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Skin%20and%20Connective%20Tissue%20Diseases Skin and Connective Tissue Diseases]: 165
 +
 
 +
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Endocrine%20System%20Diseases Endocrine System Diseases]: 129
 +
 
 +
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Cardiovascular%20Diseases Cardiovascular Diseases]: 155
 +
 
 +
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Congenital,%20Hereditary,%20and%20Neonatal%20Diseases%20and%20Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities]: 150
 +
 
 +
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Nervous%20System%20Diseases Nervous System Diseases]: 103
 +
 
 +
</div>
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|}
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 +
<!--------------main part two---------------->
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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|-
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<!-----------------Extensively curated---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
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{|style="width:100%;"
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Extensively curated</div>
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 +
|style="width:33%;|
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* [[NONHSAT028508|''HOTAIR'']]
 +
 
 +
* [[ENST00000534336.1|''MALAT-1'']]
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 +
* [[NONHSAT017465|''H19'']]
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 +
* [[NONHSAT039745|''MEG3'']]
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 +
* [[ENST00000501122.2|''NEAT1'']]
 +
 
 +
* [[ENST00000513868.2|''PVT1'']]
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 +
* [[NONHSAT007663|''GAS5'']]
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 +
* [[Lnc-C9orf53-2:1|''CDKN2B-AS1'']]
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 +
* [[NONHSAT119717|''HOTTIP'']]
  
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* [[NONHSAT113149|''7SK'']]
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 +
|style="width:33%;|
 
* [[BANCR|''BANCR'']]
 
* [[BANCR|''BANCR'']]
  
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* [[PLUT|''PLUT'']]
 
* [[PLUT|''PLUT'']]
 
* [[SMILR|''SMILR'']]
 
  
 
* [[LUNAR1|''LUNAR1'']]
 
* [[LUNAR1|''LUNAR1'']]
  
 +
* [[Lnc-SRA1-1:1|''SRA'']]
  
</td>
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|style="width:34%;|
</tr>
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* [[NONHSAT017524|''KCNQ1OT1'']]
</table>
 
</div>
 
  
|style="padding:0px 4px;"|
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* [[NONHSAT076153|''PCGEM1'']]
  
<!-----------Top 10 lncRNA-associated diseases------------>
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* [[NONHSAT137541|''XIST'']]
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [[LncRNAWiki:Disease|lncRNA-associated diseases]]</div>
 
  
<div style="padding:0.5em 0.5em;">
+
* [[Lnc-EPCAM-1:2|''BCYRN1'']]
''Diseases and their associated lncRNAs' counts are listed below.''
 
  
* [[LncRNAWiki:Cancer|Cancer]]: 212
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* [[NONHSAT084827|''TUG1'']]
  
* [[LncRNAWiki:Nervous System Diseases|Nervous System Diseases]]: 37
+
* [[Lnc-OR10H5-1:1|''UCA1'']]
  
* [[LncRNAWiki:Cardiovascular Diseases|Cardiovascular Diseases]]: 22
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* [[NONHSAT107640|''HULC'']]
  
* [[LncRNAWiki:Congenital, Hereditary, and Neonatal Diseases and Abnormalities|Congenital, Hereditary, and Neonatal Diseases and Abnormalities]]: 21
+
* [[NONHSAT129019|''PRNCR1'']]
  
* [[LncRNAWiki:Musculoskeletal Diseases|Musculoskeletal Diseases]]: 20
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* [[TP53COR1|''TP53COR1'']]
  
* [[LncRNAWiki:Hemic and Lymphatic Diseases|Hemic and Lymphatic Diseases]]: 19
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* [[Lnc-CDKN1A-1:1|''PANDAR'']]
 +
|}
  
* [[LncRNAWiki:Endocrine System Diseases|Endocrine System Diseases]]: 18
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|style="padding:0px 4px;"|
  
* [[LncRNAWiki:Mental Disorders|Mental Disorders]]: 14
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<!-----------------Function---------------------->
 +
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://bigd.big.ac.cn/lncbook/function Function]</div>
  
* [[LncRNAWiki:Skin and Connective Tissue Diseases|Skin and Connective Tissue Diseases]]: 9
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<div style="padding:0.5em 0.5em;">
 +
''Functional mechanisms and their associated lncRNAs' counts are listed below.''
  
* [[LncRNAWiki:Nutritional and Metabolic Diseases|Nutritional and Metabolic Diseases]]: 9
+
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=transcriptional%20regulation Transcriptional regulation]: 282
 +
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=ceRNA ceRNA]: 73
 +
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=translational%20control Translational control]: 13
 +
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=protein%20localization Protein localization]: 6
 +
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=splicing%20regulation Splicing regulation]: 4
  
 
</div>
 
</div>
|}
 
 
 
<!--------------main part two---------------->
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
|-
 
<!-----------------Small proteins---------------------->
 
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;45%;"|
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Small_proteins|Small proteins]]</div>
 
<div style="padding:0.5em 0.5em;">[[File:SmallPRO-5.png|center|220px|link=LncRNAWiki:Small_proteins]]</div>
 
* [[LncRNAWiki:Small_proteins|'''9,387''']] lncRNAs potentially encoding small proteins
 
 
* '''2,246''' small proteins identified with high confidence, by considering protein instability, secondary structure and transmembrane helix
 
 
|style="padding:0px 4px;"|
 
 
<!-----------------Classification---------------------->
 
 
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:54.5%;"|
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Classification|Classification]]</div>
 
<div style="padding:0.5em 0.5em;">[[File:Classification.png|center|400px|link=LncRNAWiki:Classification]]</div>
 
 
|}
 
|}
  
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* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
 
* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
  
Related publications:
+
Related publication:
* [https://www.ncbi.nlm.nih.gov/pubmed/29036542 '''Database Resources of the BIG Data Center in 2018'''.] ''Nucleic Acids Research 2018''.
+
* [https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpbi.82 '''Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook'''.] '' Curr Protoc Bioinformatics 2019''.
* [http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1060.full '''The BIG Data Center: from deposition to integration to translation'''.] (2017) ''Nucleic Acids Research'', 45:D18-24.
 
* [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 '''On the classification of long non-coding RNAs'''.] (2013) ''RNA Biology'', 10:924-933.
 
 
</div>
 
</div>
  

Latest revision as of 08:01, 16 September 2019



Welcome to LncRNAWiki
106,063 human long non-coding RNAs inside
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

LncRNAWiki, an important component of LncBook, provides community annotations of human lncRNAs
Featured-2019-3.png
Extensively curated

Functional mechanisms and their associated lncRNAs' counts are listed below.

How to Cite

If you use any data or information in your work, please cite the following publications.

Primary publication:

Related publication:

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