Difference between revisions of "Main Page"

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__NOTOC__
 
__NOTOC__
 
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__NOEDITSECTION__
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<!-----------------title--------------------->
 
<!-----------------title--------------------->
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
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|style="width:18%;|
 
|style="width:18%;|
*[[:Category:Transcripts|LncRNA Transcripts]]
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*[[:Category:Transcripts|Transcripts]]
 +
*[[:Category:Genes|Genes]]
 
*[[LncRNAWiki:Classification|Classification]]
 
*[[LncRNAWiki:Classification|Classification]]
 
|style="width:18%;|
 
|style="width:18%;|
*[[:Category:Genes|Genes]]
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*[[LncRNAWiki:Featured|Featured LncRNAs]]
*[[Special:BLAST|BLAST]]
+
*[http://bigd.big.ac.cn/lncbook/disease Disease]
|style="width:18%;|
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*[http://bigd.big.ac.cn/lncbook/function Function]
*[[LncRNAWiki:Download|Downloads]]
 
*[[LncRNAWiki:FAQ|FAQ]]
 
 
|style="width:18%;|
 
|style="width:18%;|
*[[File:New5.png]][[LncRNAWiki:Featured|Featured LncRNAs]]
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*[[LncRNAWiki:Small_proteins|Small Proteins]]
*[[File:New5.png]][[LncRNAWiki:Small_proteins|Small Proteins]]
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*[http://bigd.big.ac.cn/lgc Prediction]
*[[File:New5.png]][[LncRNAWiki:Disease|Diseases]]
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*[http://bigd.big.ac.cn/lncbook/blast BLAST]
 
|}
 
|}
 
 
<!---------------welcome Box----------------->
 
<!---------------welcome Box----------------->
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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<div style="padding:1em 0.5em;">
 
<div style="padding:1em 0.5em;">
 
{{LncRNAWiki:Summary}}
 
{{LncRNAWiki:Summary}}
<div style="padding:0.2em 0.5em;text-align:center;font-weight:bold;color:#2d2d2d;">''Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia''</div>
+
<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an important component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
 
</div>
 
</div>
 
|}
 
|}
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
|-
 
|-
 +
 +
<!-----------Featured lncRNAs------------>
 +
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
 +
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://lncrna.big.ac.cn/index.php/LncRNAWiki:Featured Featured lncRNAs]</div>
 +
<div style="padding:0.5em 0.5em;">[[File:Featured-2019-3.png|center|500px|link=LncRNAWiki:Featured]]</div>
 +
 +
|style="padding:0px 4px;"|
 +
 
<!-----------Top 10 lncRNA-associated diseases------------>
 
<!-----------Top 10 lncRNA-associated diseases------------>
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:45%;"|
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [[LncRNAWiki:Disease|lncRNA-associated diseases]]</div>
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [http://bigd.big.ac.cn/lncbook/disease lncRNA-associated diseases]</div>
  
 
<div style="padding:0.5em 0.5em;">
 
<div style="padding:0.5em 0.5em;">
 
''Diseases and their associated lncRNAs' counts are listed below.''
 
''Diseases and their associated lncRNAs' counts are listed below.''
  
* [[LncRNAWiki:Cancer|Cancer]]: 212
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Neoplasms Neoplasms]: 1,077
  
* [[LncRNAWiki:Nervous System Diseases|Nervous System Diseases]]: 37
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Digestive%20System%20Diseases Digestive System Diseases]: 427
  
* [[LncRNAWiki:Cardiovascular Diseases|Cardiovascular Diseases]]: 22
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Male%20Urogenital%20Diseases Male Urogenital Diseases]: 117
  
* [[LncRNAWiki:Congenital, Hereditary, and Neonatal Diseases and Abnormalities|Congenital, Hereditary, and Neonatal Diseases and Abnormalities]]: 21
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Female%20Urogenital%20Diseases%20and%20Pregnancy%20Complications Female Urogenital Diseases and Pregnancy Complications]: 196
  
* [[LncRNAWiki:Musculoskeletal Diseases|Musculoskeletal Diseases]]: 20
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Respiratory%20Tract%20Diseases Respiratory Tract Diseases]: 224
  
* [[LncRNAWiki:Hemic and Lymphatic Diseases|Hemic and Lymphatic Diseases]]: 19
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Skin%20and%20Connective%20Tissue%20Diseases Skin and Connective Tissue Diseases]: 165
  
* [[LncRNAWiki:Endocrine System Diseases|Endocrine System Diseases]]: 18
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Endocrine%20System%20Diseases Endocrine System Diseases]: 129
  
* [[LncRNAWiki:Mental Disorders|Mental Disorders]]: 14
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Cardiovascular%20Diseases Cardiovascular Diseases]: 155
  
* [[LncRNAWiki:Skin and Connective Tissue Diseases|Skin and Connective Tissue Diseases]]: 9
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Congenital,%20Hereditary,%20and%20Neonatal%20Diseases%20and%20Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities]: 150
  
* [[LncRNAWiki:Nutritional and Metabolic Diseases|Nutritional and Metabolic Diseases]]: 9
+
* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Nervous%20System%20Diseases Nervous System Diseases]: 103
  
 
</div>
 
</div>
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|}
  
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<!--------------main part two---------------->
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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|-
 +
 
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<!-----------------Extensively curated---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
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{|style="width:100%;"
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Extensively curated</div>
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 +
|style="width:33%;|
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* [[NONHSAT028508|''HOTAIR'']]
 +
 
 +
* [[ENST00000534336.1|''MALAT-1'']]
 +
 
 +
* [[NONHSAT017465|''H19'']]
 +
 
 +
* [[NONHSAT039745|''MEG3'']]
 +
 
 +
* [[ENST00000501122.2|''NEAT1'']]
 +
 
 +
* [[ENST00000513868.2|''PVT1'']]
  
 +
* [[NONHSAT007663|''GAS5'']]
  
<!-----------Featured lncRNAs------------>
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* [[Lnc-C9orf53-2:1|''CDKN2B-AS1'']]
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:54.5%;"|
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Featured|Featured lncRNAs]]</div>
 
<div style="padding:0.5em 0.5em;">
 
<table>
 
<tr>
 
<td>[[File:Featured4.png|left|430px|link=LncRNAWiki:Featured]]</td>
 
<td valign="top">
 
Extensively curated:
 
  
* [[ENST00000609176.1|''AIRN'']]
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* [[NONHSAT119717|''HOTTIP'']]
  
* [[ENST00000444200.1|''APOA1-AS'']]
+
* [[NONHSAT113149|''7SK'']]
  
 +
|style="width:33%;|
 
* [[BANCR|''BANCR'']]
 
* [[BANCR|''BANCR'']]
  
* [[ENST00000502056.1|''CASC8'']]
+
* [[BTG3-AS1|''BTG3-AS1'']]
 +
 
 +
* [[CERNA2|''CERNA2'']]
 +
 
 +
* [[FLICR|''FLICR'']]
 +
 
 +
* [[GUARDIN|''GUARDIN'']]
 +
 
 +
* [[LINC-ROR|''LINC-ROR'']]
 +
 
 +
* [[PINCR|''PINCR'']]
 +
 
 +
* [[PLUT|''PLUT'']]
 +
 
 +
* [[LUNAR1|''LUNAR1'']]
 +
 
 +
* [[Lnc-SRA1-1:1|''SRA'']]
  
* [[NONHSAT017465|''H19'']]
+
|style="width:34%;|
 +
* [[NONHSAT017524|''KCNQ1OT1'']]
 +
 
 +
* [[NONHSAT076153|''PCGEM1'']]
 +
 
 +
* [[NONHSAT137541|''XIST'']]
 +
 
 +
* [[Lnc-EPCAM-1:2|''BCYRN1'']]
 +
 
 +
* [[NONHSAT084827|''TUG1'']]
  
* [[NONHSAT028508|''HOTAIR'']]
+
* [[Lnc-OR10H5-1:1|''UCA1'']]
  
* [[ENST00000511918.1|''LUCAT1'']]
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* [[NONHSAT107640|''HULC'']]
  
* [[ENST00000513868.2|''PVT1'']]
+
* [[NONHSAT129019|''PRNCR1'']]
  
* [[ENST00000534336.1|''MALAT-1'']]
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* [[TP53COR1|''TP53COR1'']]
  
* [[NONHSAT039745|''MEG3'']]
+
* [[Lnc-CDKN1A-1:1|''PANDAR'']]
</td>
 
</tr>
 
</table>
 
</div>
 
 
|}
 
|}
  
<!--------------main part two---------------->
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|style="padding:0px 4px;"|
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
|-
 
<!-----------------Small proteins---------------------->
 
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;45%;"|
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Small_proteins|Small proteins]]</div>
 
<div style="padding:0.5em 0.5em;">[[File:SmallPRO-5.png|center|220px|link=LncRNAWiki:Small_proteins]]</div>
 
* [[LncRNAWiki:Small_proteins|'''9,387''']] lncRNAs potentially encoding small proteins
 
  
* '''2,246''' small proteins identified with high confidence, by considering protein instability, secondary structure and transmembrane helix
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<!-----------------Function---------------------->
 +
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://bigd.big.ac.cn/lncbook/function Function]</div>
  
|style="padding:0px 4px;"|
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<div style="padding:0.5em 0.5em;">
 +
''Functional mechanisms and their associated lncRNAs' counts are listed below.''
  
<!-----------------Classification---------------------->
+
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=transcriptional%20regulation Transcriptional regulation]: 282
 +
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=ceRNA ceRNA]: 73
 +
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=translational%20control Translational control]: 13
 +
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=protein%20localization Protein localization]: 6
 +
* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=splicing%20regulation Splicing regulation]: 4
  
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:54.5%;"|
+
</div>
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Classification|Classification]]</div>
 
<div style="padding:0.5em 0.5em;">[[File:Classification.png|center|400px|link=LncRNAWiki:Classification]]</div>
 
 
|}
 
|}
  
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* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
 
* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
  
Related publications:
+
Related publication:
* [http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1060.full '''The BIG Data Center: from deposition to integration to translation'''.] (2017) ''Nucleic Acids Research'', 45:D18-24.
+
* [https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpbi.82 '''Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook'''.] '' Curr Protoc Bioinformatics 2019''.
* [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 '''On the classification of long non-coding RNAs'''.] (2013) ''RNA Biology'', 10:924-933.
 
 
</div>
 
</div>
  

Latest revision as of 08:01, 16 September 2019



Welcome to LncRNAWiki
106,063 human long non-coding RNAs inside
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

LncRNAWiki, an important component of LncBook, provides community annotations of human lncRNAs
Featured-2019-3.png
Extensively curated

Functional mechanisms and their associated lncRNAs' counts are listed below.

How to Cite

If you use any data or information in your work, please cite the following publications.

Primary publication:

Related publication:

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