Difference between revisions of "Main Page"

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__NOTOC__
 
__NOTOC__
 
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<!-----------------title--------------------->
 
<!-----------------title--------------------->
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 
{|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
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|style="width:18%;|
 
|style="width:18%;|
*[[:Category:Transcripts|LncRNA Transcripts]]
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*[[:Category:Transcripts|Transcripts]]
 +
*[[:Category:Genes|Genes]]
 
*[[LncRNAWiki:Classification|Classification]]
 
*[[LncRNAWiki:Classification|Classification]]
 
|style="width:18%;|
 
|style="width:18%;|
*[[:Category:Genes|Genes]]
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*[[LncRNAWiki:Featured|Featured LncRNAs]]
*[[Special:BLAST|BLAST]]
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*[http://bigd.big.ac.cn/lncbook/disease Disease]
|style="width:18%;|
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*[http://bigd.big.ac.cn/lncbook/function Function]
*[[LncRNAWiki:Download|Downloads]]
 
*[[LncRNAWiki:FAQ|FAQ]]
 
 
|style="width:18%;|
 
|style="width:18%;|
*[[File:New5.png]][[LncRNAWiki:Featured|Featured LncRNAs]]
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*[[LncRNAWiki:Small_proteins|Small Proteins]]
*[[File:New5.png]][[LncRNAWiki:Small_proteins|Small Proteins]]
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*[http://bigd.big.ac.cn/lgc Prediction]
*[[File:New5.png]][[LncRNAWiki:Disease|Diseases]]
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*[http://bigd.big.ac.cn/lncbook/blast BLAST]
 
|}
 
|}
 
 
<!---------------welcome Box----------------->
 
<!---------------welcome Box----------------->
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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<div style="padding:1em 0.5em;">
 
<div style="padding:1em 0.5em;">
 
{{LncRNAWiki:Summary}}
 
{{LncRNAWiki:Summary}}
<div style="padding:0.2em 0.5em;text-align:center;font-weight:bold;color:#2d2d2d;">''Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia''</div>
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<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an important component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
 
</div>
 
</div>
----
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|}
  
|}
 
 
<!--------------main part one---------------->
 
<!--------------main part one---------------->
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 
|-
 
|-
  
 +
<!-----------Featured lncRNAs------------>
 +
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
 +
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://lncrna.big.ac.cn/index.php/LncRNAWiki:Featured Featured lncRNAs]</div>
 +
<div style="padding:0.5em 0.5em;">[[File:Featured-2019-3.png|center|500px|link=LncRNAWiki:Featured]]</div>
  
<!-----------Top 10 diseases------------>
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|style="padding:0px 4px;"|
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:45%;"|
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10 diseases</div>
 
  
* 212 [[LncRNAWiki:Cancer|Cancer]]
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<!-----------Top 10 lncRNA-associated diseases------------>
 +
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [http://bigd.big.ac.cn/lncbook/disease lncRNA-associated diseases]</div>
  
* 37 [[LncRNAWiki:Nervous System Diseases|Nervous System Diseases]]
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<div style="padding:0.5em 0.5em;">
 +
''Diseases and their associated lncRNAs' counts are listed below.''
  
* 22 [[LncRNAWiki:Cardiovascular Diseases|Cardiovascular Diseases]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Neoplasms Neoplasms]: 1,077
  
* 21 [[LncRNAWiki:Congenital, Hereditary, and Neonatal Diseases and Abnormalities|Congenital, Hereditary, and Neonatal Diseases and Abnormalities]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Digestive%20System%20Diseases Digestive System Diseases]: 427
  
* 20 [[LncRNAWiki:Musculoskeletal Diseases|Musculoskeletal Diseases]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Male%20Urogenital%20Diseases Male Urogenital Diseases]: 117
  
* 19 [[LncRNAWiki:Hemic and Lymphatic Diseases|Hemic and Lymphatic Diseases]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Female%20Urogenital%20Diseases%20and%20Pregnancy%20Complications Female Urogenital Diseases and Pregnancy Complications]: 196
  
* 18 [[LncRNAWiki:Endocrine System Diseases|Endocrine System Diseases]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Respiratory%20Tract%20Diseases Respiratory Tract Diseases]: 224
  
* 14 [[LncRNAWiki:Mental Disorders|Mental Disorders]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Skin%20and%20Connective%20Tissue%20Diseases Skin and Connective Tissue Diseases]: 165
  
* 9 [[LncRNAWiki:Skin and Connective Tissue Diseases|Skin and Connective Tissue Diseases]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Endocrine%20System%20Diseases Endocrine System Diseases]: 129
  
* 9 [[LncRNAWiki:Nutritional and Metabolic Diseases|Nutritional and Metabolic Diseases]]
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Cardiovascular%20Diseases Cardiovascular Diseases]: 155
  
''Top diseases and the lncRNA numbers are listed.''
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Congenital,%20Hereditary,%20and%20Neonatal%20Diseases%20and%20Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities]: 150
  
|style="padding:0px 4px;"|
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* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Nervous%20System%20Diseases Nervous System Diseases]: 103
 +
 
 +
</div>
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|}
  
 +
<!--------------main part two---------------->
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{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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|-
  
<!-----------Featured lncRNAs------------>
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<!-----------------Extensively curated---------------------->
 
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
 
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Featured lncRNAs</div>
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{|style="width:100%;"
<div style="padding:0.5em 0.5em;">
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Extensively curated</div>
<table>
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<tr>
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|style="width:33%;|
<td>[[File:Featured2.png|left|410px|caption]]</td>
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* [[NONHSAT028508|''HOTAIR'']]
<td valign="top">
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* XXX
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* [[ENST00000534336.1|''MALAT-1'']]
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 +
* [[NONHSAT017465|''H19'']]
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 +
* [[NONHSAT039745|''MEG3'']]
 +
 
 +
* [[ENST00000501122.2|''NEAT1'']]
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 +
* [[ENST00000513868.2|''PVT1'']]
 +
 
 +
* [[NONHSAT007663|''GAS5'']]
 +
 
 +
* [[Lnc-C9orf53-2:1|''CDKN2B-AS1'']]
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 +
* [[NONHSAT119717|''HOTTIP'']]
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 +
* [[NONHSAT113149|''7SK'']]
 +
 
 +
|style="width:33%;|
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* [[BANCR|''BANCR'']]
 +
 
 +
* [[BTG3-AS1|''BTG3-AS1'']]
 +
 
 +
* [[CERNA2|''CERNA2'']]
 +
 
 +
* [[FLICR|''FLICR'']]
 +
 
 +
* [[GUARDIN|''GUARDIN'']]
 +
 
 +
* [[LINC-ROR|''LINC-ROR'']]
 +
 
 +
* [[PINCR|''PINCR'']]
 +
 
 +
* [[PLUT|''PLUT'']]
 +
 
 +
* [[LUNAR1|''LUNAR1'']]
 +
 
 +
* [[Lnc-SRA1-1:1|''SRA'']]
 +
 
 +
|style="width:34%;|
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* [[NONHSAT017524|''KCNQ1OT1'']]
 +
 
 +
* [[NONHSAT076153|''PCGEM1'']]
 +
 
 +
* [[NONHSAT137541|''XIST'']]
 +
 
 +
* [[Lnc-EPCAM-1:2|''BCYRN1'']]
 +
 
 +
* [[NONHSAT084827|''TUG1'']]
 +
 
 +
* [[Lnc-OR10H5-1:1|''UCA1'']]
  
* XXX
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* [[NONHSAT107640|''HULC'']]
  
* XXX
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* [[NONHSAT129019|''PRNCR1'']]
  
* XXX
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* [[TP53COR1|''TP53COR1'']]
</td>
 
</tr>
 
</table>
 
</div>
 
  
 +
* [[Lnc-CDKN1A-1:1|''PANDAR'']]
 
|}
 
|}
  
<!--------------main part two---------------->
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|style="padding:0px 4px;"|
{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
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|-
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<!-----------------Function---------------------->
<!-----------------Classification---------------------->
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|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:55%;"|
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://bigd.big.ac.cn/lncbook/function Function]</div>
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div>
 
<div style="padding:0.5em 0.5em;">[[File:web2a.png|left|410px]]
 
LncRNAs are classified into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). [[Help:Contents#Database content|''Help'']]
 
<br /></div>
 
  
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<div style="padding:0.5em 0.5em;">
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''Functional mechanisms and their associated lncRNAs' counts are listed below.''
  
<!-----------------Small proteins---------------------->
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=transcriptional%20regulation Transcriptional regulation]: 282
|valign="top" style="border:1px solid #66B3FF; background-color:transparent;45%;"|
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=ceRNA ceRNA]: 73
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Small proteins</div>
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=translational%20control Translational control]: 13
<div style="padding:0.5em 0.5em;">[[File:SmallPRO-1.png|left|330px]]  
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=protein%20localization Protein localization]: 6
'''9,387''' lncRNAs potentially encoding small proteins and '''2,246''' among them are with high confidence ([[LncRNAWiki:small proteins|lncRNAs and small proteins]]). [[Help:Contents#Database content|''Help'']]
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* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=splicing%20regulation Splicing regulation]: 4
<br /></div>
 
  
 +
</div>
 
|}
 
|}
  
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<div style="padding:0.5em 1em;">
 
<div style="padding:0.5em 1em;">
 
If you use any data or information in your work, please cite the following publications.
 
If you use any data or information in your work, please cite the following publications.
 +
 
Primary publication:
 
Primary publication:
 
* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
 
* [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
  
Related publications:
+
Related publication:
* [http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1060.full '''The BIG Data Center: from deposition to integration to translation'''.] ''Nucleic Acids Research'' 2017, accepted and in press.
+
* [https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpbi.82 '''Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook'''.] '' Curr Protoc Bioinformatics 2019''.
* [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 '''On the classification of long non-coding RNAs'''.] (2013) ''RNA Biology'', 10(6),924-933.
 
 
</div>
 
</div>
  

Latest revision as of 08:01, 16 September 2019



Welcome to LncRNAWiki
106,063 human long non-coding RNAs inside
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

LncRNAWiki, an important component of LncBook, provides community annotations of human lncRNAs
Featured-2019-3.png
Extensively curated

Functional mechanisms and their associated lncRNAs' counts are listed below.

How to Cite

If you use any data or information in your work, please cite the following publications.

Primary publication:

Related publication:

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