Difference between revisions of "Main Page"

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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Featured lncRNAs</div>
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Featured lncRNAs</div>
<div style="padding:0.5em 0.5em;">[[File:Featured2.png|left|560px|caption]]  
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<div style="padding:0.5em 0.5em;">[[File:Featured2.png|left|410px|caption]]  
===<u>Top 10 Diseases</u>===
 
  
213 Cancer 39 Nervous System Diseases
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LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. In contrast to the previous version that had 86 curated lncRNAs, the updated version has a total of 948 lncRNAs that are community-curated ([[LncRNAWiki:Featured|Featured lncRNAs]]).
  
33 Congenital, Hereditary, and Neonatal Diseases 21 Musculoskeletal Diseases
 
  
21 Hemic and Lymphatic Diseases 21 Mental Disorders
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19 Cardiovascular Diseases 15 Nutritional and Metabolic Diseases
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15 Endocrine System Diseases 10 Skin and Connective Tissue Diseases
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Diseases</div>
 
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===<u>Top 10 Diseases</u>===
===<u>Top 10 Cancers</u>===
 
  
46 [[LncRNAWiki:gastric-cancer|Gastric Cancer]] 45 [[LncRNAWiki:breast-cancer|Breast Cancer]]
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* 213 Cancer  
  
45 [[LncRNAWiki:lung-adenocarcinoma|Lung Cancer]] 34 [[LncRNAWiki:hepatocellular-carcinoma|Hepatocellular Carcinoma]]
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* 39 Nervous System Diseases
  
34 [[LncRNAWiki:prostate-cancer|Prostate Cancer]] 32 [[LncRNAWiki:colorectal-cancer|Colorectal Cancer]]
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* 33 Congenital, Hereditary, and Neonatal Diseases
  
23 [[LncRNAWiki:esophageal-carcinoma|Esophageal Carcinoma]] 15 [[LncRNAWiki:ovarian-cancer|Ovarian Cancer]]
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* 21 Musculoskeletal Diseases
  
14 [[LncRNAWiki:bladder-cancer|Bladder Cancer]] 14 [[LncRNAWiki:glioma|Glioma]]
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* 21 Hemic and Lymphatic Diseases 21 Mental Disorders
  
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* 19 Cardiovascular Diseases 15 Nutritional and Metabolic Diseases
  
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* 15 Endocrine System Diseases 10 Skin and Connective Tissue Diseases
  
LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. In contrast to the previous version (released in 2014) that had 86 curated lncRNAs, the 2017 updated version has, a total of 948 lncRNAs that are community-curated ([[LncRNAWiki:Featured|Featured LncRNAs]]).
 
  
 
Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases  ([[LncRNAWiki:Disease|Disease]]).
 
Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases  ([[LncRNAWiki:Disease|Disease]]).
  
''Top diseases and top cancers, and the lncRNA numbers are listed.''
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''Top diseases and the lncRNA numbers are listed.''
  
 
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Revision as of 03:39, 29 June 2017


Welcome to LncRNAWiki
106,053 human long non-coding RNAs inside
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia

Featured lncRNAs
caption

LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. In contrast to the previous version that had 86 curated lncRNAs, the updated version has a total of 948 lncRNAs that are community-curated (Featured lncRNAs).



Diseases

Top 10 Diseases

  • 213 Cancer
  • 39 Nervous System Diseases
  • 33 Congenital, Hereditary, and Neonatal Diseases
  • 21 Musculoskeletal Diseases
  • 21 Hemic and Lymphatic Diseases 21 Mental Disorders
  • 19 Cardiovascular Diseases 15 Nutritional and Metabolic Diseases
  • 15 Endocrine System Diseases 10 Skin and Connective Tissue Diseases


Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases (Disease).

Top diseases and the lncRNA numbers are listed.

Classification
Web2a.png

The majority of the lncRNA information was initially seeded with a subset of information from GENCODE, NONCODE, LNCipedia, and lncRNAdb, and we classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). Help



Small proteins
SmallPRO-1.png

We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki.

As a result, we identified 9,387 lncRNAs potentially encoding small proteins and 2,246 among them are with high confidence (lncRNAs and small proteins, Help).


How to Cite

If you use any data or information in your work, please cite the following primary publication:

Related publication:

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