Difference between revisions of "Main Page"

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===<u>Top 10 Cancers</u>===
 
===<u>Top 10 Cancers</u>===
  
36 Breast Cancer
+
46 Gastric Cancer
  
31 Prostate Cancer
+
45 [[LncRNAWiki:breast-cancer|Breast Cancer]]
  
30 Hepatocellular Carcinoma
+
45 [[LncRNAWiki:lung-adenocarcinoma|Lung Cancer]]
  
28 Gastric Cancer
+
34 [[LncRNAWiki:hepatocellular-carcinoma|Hepatocellular Carcinoma]]
  
26 Lung Cancer
+
34 [[LncRNAWiki:prostate-cancer|Prostate Cancer]]
  
18 Colorectal Cancer
+
32 [[LncRNAWiki:colorectal-cancer|Colorectal Cancer]]
  
12 Esophageal Squamous Cell Carcinoma
+
23 [[LncRNAWiki:esophageal-carcinoma|Esophageal Carcinoma]]
  
12 Bladder Cancer
+
15 [[LncRNAWiki:ovarian-cancer|Ovarian Cancer]]
  
9 Glioma
+
14 [[LncRNAWiki:bladder-cancer|Bladder Cancer]]
  
9 Lung Adenocarcinoma
+
14 [[LncRNAWiki:glioma|Glioma]]
  
 
Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases  ([[LncRNAWiki:Disease|Disease]]).
 
Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases  ([[LncRNAWiki:Disease|Disease]]).

Revision as of 09:58, 28 June 2017


Welcome to LncRNAWiki
105,824 human long non-coding RNAs inside
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia

Disease
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Top 10 Diseases

213 Neoplasms

39 Nervous System Diseases

33 Congenital, Hereditary, and Neonatal Diseases

21 Musculoskeletal Diseases

21 Hemic and Lymphatic Diseases

21 Mental Disorders

19 Cardiovascular Diseases

15 Nutritional and Metabolic Diseases

15 Endocrine System Diseases

10 Skin and Connective Tissue Diseases

Top 10 Cancers

46 Gastric Cancer

45 Breast Cancer

45 Lung Cancer

34 Hepatocellular Carcinoma

34 Prostate Cancer

32 Colorectal Cancer

23 Esophageal Carcinoma

15 Ovarian Cancer

14 Bladder Cancer

14 Glioma

Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases (Disease).

Top diseases and top cancers, and the lncRNA numbers are listed.

Classification
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The majority of the lncRNA information was initially seeded with a subset of information from GENCODE, NONCODE, LNCipedia, and lncRNAdb, and we classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). Help


Featured lncRNA
caption

LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence.

In contrast to the previous version (released in 2014) that had 86 curated lncRNAs, the 2017 updated version has, a total of 948 lncRNAs that are community-curated (Featured LncRNAs).


Small protein
SmallPRO-1.png

We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki.

As a result, we identified 9,387 lncRNAs potentially encoding small proteins and 2,246 among them are with high confidence (lncRNAs and small proteins, Help).


How to Cite

If you use any data or information in your work, please cite the following primary publication:

Related publication:

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