TNFRSF10A-AS1:TNFRSF10A antisense RNA 1
RP11-1149O23.2 is localized at the minus strand relative to a protein-coding gene TNFRSF10A, the protein of which is a pro-apoptosis receptor to mediate the extrinsic apoptosis pathway.
RP11-1149O23.2 has a high coexpression coefcient of 0.81 with TNFRSF10A, suggesting the possibility of RP11-1149O23.2 in cis-regulation of TNFRSF10A. In addition, RP11-1149O23.2 is signifcantly associated with the overall survival of patientswith gastric cancer.
Labs working on this lncRNA
- Department of Gastrointestinal Surgery, The First Hospital of Jilin University, Changchun, Jilin, China (mainland).
- Ren W, Zhang J, Li W, Li Z, Hu S, Suo J, Ying X. A Tumor-Specific Prognostic Long Non-Coding RNA Signature in Gastric Cancer. Med Sci Monit. 2016 Oct 11;22:3647-3657.