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mascRNA: MALAT1-associated small cytoplasmic RNA
mascRNA is a conserved, 61 nucleotide, tRNA-like sequence at the 3' end of Malat1 that is cleaved off the full length transcript and processed to generate a short tRNA-like ncRNA.
Mature mascRNA undergoes a post-transcriptional CCA addition and folds into a tRNA like structure but could not be amino acylated.
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mascRNA was cleaved off Malat1 in a wide variety of human tissues.
mascRNA is cleaved off Malat1 by RNaseP in the nucleus before further processing by RNaseZ and then exported to the cytoplasm.
Conserved in mammals and back to reptiles and amphibians. More highly conserved than most of Malat1.
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Allelic Information and Variation
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Labs working on this lncRNA
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