ENST00000426539.1

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GACAT3, gastric cancer associated transcript 3, plays crucial role during cancer progression and may be a potential tumor marker for gastric cancer.

Annotated Information

Transcriptomic Nomeclature

GACAT3, gastric cancer associated transcript 3 (HGNC nomenclature)

lncRNA-AC130710[1]

Function

As one of lncRNAs, GACAT3 was up-expressed in gastric cancer. Its levels were associated with tumor size, TNM stages, distal metastasis, and tissue CEA expression, which suggested that lncRNA-AC130710 plays crucial role during cancer progression and may be a potential tumor marker for gastric cancer[1].

Regulation

miR-129-5p may play an important role in the down-regulating of GACAT3 expression in gastric cancer cells[1].

Expression

GACAT3 expression levels in gastric cancer tissues and adjacent normal tissues[1]

AC130710 was upregulated in the gastric cancer tissues and gastric cancer lines[1].

Primer Sense Antisense
GAPDH 5'-GGGGGCTTGTTTCTTTGTGTAG-3' 5'-CATTCGGCTCTGACCTCTCAC-3'[1]
GACAT3 5'-ACCCACTCCTCCACCTTTGAC-3' 5'-TGTTGCTGTAGCCAAAATTCGTT-3'[1]

Diseases

Gastric cancer[1]


Labs working on this lncRNA

Department of Biochemistry and Molecular Biology, Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo, 315211, China[1].

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Xu C, Shao Y, Xia T, Yang Y, Dai J, Luo L, et al. lncRNA-AC130710 targeting by miR-129-5p is upregulated in gastric cancer and associates with poor prognosis[J]. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014,35(10):9701-6.

Basic Information

Transcript ID

ENST00000426539.1

Source

Gencode19

Same with

lnc-MYCN-2:1,NONHSAT069315,GACAT3,lncRNA-AC130710

Classification

intergenic

Length

1096 nt

Genomic location

chr2+:16190549..16225923

Exon number

4

Exons

16190549..16190799,16213426..16213564,16221020..16221212,16225411..16225923

Genome context

Sequence
000001 CTGACCACAG GCTTTGGTTT CAGGACAATG CAGACTGGGC AGCAGATCAA ATAAAGCCAT CACCAGCGCA TAGGACAGTC 000080
000081 TCAAGGGGGT TAACTGTCCC TGTCCTCTAC AATTGTTGCT GGGGAGCAAT TTGCCCTTGA ATCTTCCATA CTGTCCCTAA 000160
000161 ATTGACAATT TCATTTCCTT CCAATCCCGC CCCCTGCCCT GAAGATCTGC TGAGGCTGCG AGTTCCATGT GAGAAGGCAG 000240
000241 GAGGATAATA GCCAGCTCCT GTGTAAGGAA GTCAAGATTT TCTCAAGGGA AAAATCACCC TAGAAACCAT CAACTCATGA 000320
000321 CAAACGTGAT CTCCAACGTT CATTGTGGAA AATAGCCTCA AGGATGAGAT GATGAGGATT TTGAAGATGG GTCTTAAGAG 000400
000401 AAAACACTGA GGTCCCTCGA AGATGAAGAA ATCCTCATGA AGATGAATCC AAAGGTGGAT TCAATTTCAG CTGTCTTTGG 000480
000481 ACTGAAGACT GCAACATCAA CACTTCCCAG GGTCTCCAGC CTGCCCGCCT CTCCCGCAAA TTTCAGATTT GCAAGTATCC 000560
000561 ACAGTCATGA GCAATTCCTT AAATGAAGTG CAAAAAATGA ACAAGGAGGC CCAATGATGC ATCTGCTTAA CTTTTCAGTT 000640
000641 GTCAATGCAA ATTAAGCACA AAGAGGACAG AGTTGATGAC ATATCAGGAA CATTTTTTAC TTCCGGAGCA GGTCTGAGTC 000720
000721 CCAGCGGAAG ACTGAGGCCG ACTGAGCCAG AGGCACCACT TCAATAGGTC ACTGGTCTCT GCAGGGAAAG GAAAAGGTGT 000800
000801 AAGAGTTCTC CCTGCATAGA TGCTATTTGT GACTTGGATG TTTTCTTTCT AATACAAATG CATCAAAGTG TTCACAGGAA 000880
000881 TCTAGCTATA TGCAAGAAGT CTGGATTATC TGCCTGAGAG AACTGGCCAG TATCTCACCC ATGAGCACCA GAACCCATTT 000960
000961 CTAGATTACT AAGAAAGGAG CACAAGAACA CTGTGTATAA GGCTCTGTGT TCCTAGAACT TTCTAAATTT TACTTAATGC 001040
001041 AGGTTAACTT CATCAACCCT GGTGAAAATG CCACCTCCTC ATGAGGAAGC CTTCCC
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Internal error

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[XfURwt77apeu0r0dvKd@5QAAAAY] 2019-12-14 16:45:56: Fatal exception of type "TypeError"

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