TNFRSF10A-AS1

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Annotated Information

Name

TNFRSF10A-AS1:TNFRSF10A antisense RNA 1

RP11-1149O23.2[1]

Characteristics

RP11-1149O23.2 is localized at the minus strand relative to a protein-coding gene TNFRSF10A, the protein of which is a pro-apoptosis receptor to mediate the extrinsic apoptosis pathway.[1]

Function

RP11-1149O23.2 has a high coexpression coefcient of 0.81 with TNFRSF10A, suggesting the possibility of RP11-1149O23.2 in cis-regulation of TNFRSF10A. In addition, RP11-1149O23.2 is signifcantly associated with the overall survival of patientswith gastric cancer.[1]

Diseases

Gastric cancer[1]

Labs working on this lncRNA

  • Department of Gastrointestinal Surgery, The First Hospital of Jilin University, Changchun, Jilin, China (mainland).

References

  1. 1.0 1.1 1.2 1.3 Ren W, Zhang J, Li W, Li Z, Hu S, Suo J, Ying X. A Tumor-Specific Prognostic Long Non-Coding RNA Signature in Gastric Cancer. Med Sci Monit. 2016 Oct 11;22:3647-3657.