SLC7A11-AS1

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Annotated Information

The role of the SLC7A11-AS1–SC7A11 model interacts in tumor development[1].
SLC7A11-AS1 expression levels were assessed in human gastric cancer tissues and PBMCs[1].

Name

Approved Symbol: SLC7A11-AS1

Approved Name: SLC7A11 antisense RNA 1

Synonyms: ENST00000512786

Chromosome:4q28.3

RefSeq ID: NR_038380

LncBook transcript ID: HSALNT0078323

Characteristics

-

Function

  • SLC7A11-AS1, antisense to SLC7A11, could promote tumor growth in vitro and in vivo. The effects of SLC7A11-AS1 depend on the regulation of SLC7A11 via the ASK1-p38MAPK/JNK signaling pathway[1].

Regulation

-

Diseases

Gastric Cancer[1].

Expression

SLC7A11-AS1 is significantly down-regulated in gastric cancer [1].

Evolution

-

pubmed IDs

27816668, 29348845

Sequence

>NR_038380.1 Homo sapiens SLC7A11 antisense RNA 1 (SLC7A11-AS1), long non-coding RNA

000001 TCTGTCTGGC AAGCGCCGCG CGCATCCTCG GTTCCCGCCG CGCCGTTGCC GCCGCTCCTC TCCCTCCTCA CCTCCCCGCA 000080
000081 AGCTGAGGGA GCCGGCTCTG GCCTTGGCCA GCCCAGAAAG GGGCTCCCAC AGTGCAGCGG TGAGCTGAAG GGTTCCTCAA 000160
000161 GCGCGGCCAG AGTGGGCGCC AAGGCCGAGG AGGCGCCCAG AGCCAGCGAG GGCTGCCAGC AAGCTGTCAC CTCTCAATAG 000240
000241 GAACTGGTAC CAACCTACTT ACGAAGAAGT ATTTGTTTTA ACCTGAACCT GGGGGAAAAA CAACATGAAC TGTTCGTCTA 000320
000321 TCTATATCGT CATTATTTTT TACCTCATGG ATTGAAACAA ATTTTAAAGG AAAAAAGAAT GTTAAGAAAG AGCAGCACTT 000400
000401 ACTATCAGGG AGGCACCTCA CGAGCATTGT AAACACTCAG GCTCGCTGCT TTCTGAAGGA CATGCCAATC ATGCACAGCA 000480
000481 CTTACTAGAA ACTGCAAGAC TGCACAACAT GATGGTATTT ATTCCAGGAA CAGGAGCCAG TCCTGGGCAC ACACATAAAG 000560
000561 GGACTTCCTT CACTCCCCAG AAGAAGAGAA AGCATGCTGA CACACATCTG CCCAAGCAAT CAGAAGGCAG CTAAAGCCGC 000640
000641 CACAGTCTTC ACTCACCAAC AGTTAGACCT TTTCAATTGA TTTTATTGAA GAAAGTGAGT GCTGAGCACC ATGAGTTCTC 000720
000721 ATAAACAATC CATTTTGGCA AATGCTTTAA GAATGTTGGT TAATTGCAGT TAGGCAGCAT CGACGTATTT TATTTTTTGG 000800
000801 AAAGCAAGAA GCTGGCTTAC CAACATTAAG TTAAACAACA TGTAAGGGTT AGAAATATGA ATCAACAAAC TATTAGGGTG 000880
000881 GTACCATCTC TTTATAATAA AACAATGTAG ATTGATTAAG TATAGCCTAA AAGTTTACCA CAAATCATAA CTACATTTAA 000960
000961 GCTTTGAATT TCATGACTAG TGATTAATTT TGCATGTCAA CTTGACTGAG CTTATAGAAT GCCCAGGTAT CTGATTAAAC 001040
001041 GTTATTTCTG GAGGTGTCTG TGAGGGTGTT TCTGTAAGAG ATTAGCATCT GAAGGCCAGG TGTGGTGGCT CATGCCTGTA 001120
001121 ATCCTAGTAC TTTGGGAGGC CGAGGTGGGC AGATTGCCTG AGCTCAGGAG TCTGAGACCA GCCTGGGCAA CATGGCAAAA 001200
001201 CACCGTCTGT ACTAAAAAAT ACAAAGTTTA GCCGGATGTG GTGGCACACA CCTGTAGTCC CAGCTACTAG GGAGGCTAAG 001280
001281 GCATGAGAAT TTCCTGAGCC TGCGAGGCGG AGGTTGTGGT AAGCCAAGAT TGTACTCCAG CCTGGGTGAT AAAGTGAGAC 001360
001361 CCTATCTCAT AAAAAACAAA AAAACAAAAA AGAAAAAAGG AGAAGAAAGA GACACAGATT AGCATTTGAA TGGGTGGACT 001440
001441 GAGTAAAGCA GATGGCCCTC GTCAGTGTTG GTGGGAATTG TCCTATCCAT TGAGGGCTTA AATGAAACAA AGACTGAGGA 001520
001521 AGGCTGAATT CAATCTCTGC TGACTGCTGG GGCTGAGACA TCAATCTTCT CCGGCTCTCA GTGCTCTTCC AGACTCAGAC 001600
001601 TGGAATGTAC ACTATCAGCT CTCCAGTTCT CAGGCCTTCA AATTACACCT CTGGCTTTCC TGGGTCTCCA GCTTGCAGAT 001680
001681 GGCAGATCGT GGGACTTCAT GGGACTTCTC AGACTCCATA ACCAAGGCTG AGGAGCTACA GTCTAAATGC ATACGCATGT 001760
001761 TGGGAACCGA AGTCAGCCAT CTTCCCTAGG ACAAATCTTT ACTCTTCTAA AGAAGGACAA GAATAAGAAT TGAAAACACT 001840
001841 TTTCACAGTA TAGACATCTA TAGTGTGTAA AACCATCTTT ACAAAACCCA TATATACAGA AAAATCTCAG TCTTCAATTT 001920
001921 GAAGGTTCTT TGCCGTGCTA ACATATGTTG TAGAGAATGA CCACATAGTA ATTGTCTAGT CTTTTCTCCT AACCCCAATA 002000
002001 GGATTTGAAT GACTTTCATC GTAATGAAGG CTTCTGCAGA GTAATTGATT TTGACCATGA GTACCTGTTG AAGTCACAGC 002080
002081 AACTTCTCCT TCTAGATTAT CTTACAGCAG TGGACCAGAC AGCAGTGCTC AAGAGAGAAA TGCTATCAAA CAAAAAGTGG 002160
002161 TTCAATACTG GCATCCTGTG GCTGGAGAGA TTTATCAAAT CTCTGAAAAT CTCAGCTCCT TGGATTCTGA ACATTCCCTG 002240
002241 GCTGTCAGTT CTCAGCAGCC TTTCACCATT TTCCGAGTGC TATTTGGTTA CCTCTCATTT TTCATGGAAA CAACCTAGGT 002320
002321 AAAATGCATT TTGATAGACT ATCATTTTCA CAGGGCTGAT CTACTCATGC ATTATCAGGG TAAAAATAAA TGATAATATA 002400
002401 AAGGTTTTGG AATTTTACCT AATGAAAGAA CATGATATTA AATCATTGAA CAAACTGCTC CAAGCAAAGG CTCTTGGTCT 002480
002481 CTAAGTTCAC ATTGAGTTTC TCTCTAACAA AATGATCATA GAGTAGTTGG GAGAAGGGAC AGGGCGCTGC TTCAGGATTT 002560
002561 TGTTGTTTGT GCGTCTGTGT GTGAGTGTTT TGTTTTGGCC AAAGGCTAAG AAAATACTTC CTATTGCAGC AATAAATATT 002640
002641 ATGAATTTTC TTTATTTTAC TACAAGAATG CTGCCTCAGA GAAAAATCAA ACAAAATTAC GGAGGACTGT TGCTTTTTGC 002720
002721 TACTCACTTT CAAGGCAGCT ATAAAGATAA AGAGTTACAA TGATCGCAGT TTAAAAGCAG AATTGCCATG CTCCCTGGTA 002800
002801 AGACTTAATG GCATTTTTGA GAACCAAATA ACCATTATGG GACTACTCCA TTGCTGCTAG TTTCACAAAT GGCTAACACT 002880
002881 AAATTTGGAG GCCTTGGAAA TGTTCAAAAC ATCATTAGAG ATAGAAAAAT AGCAACAAAC TTTAAAATTA CATGAACACC 002960
002961 AAAAGACATC AATGAAGGAT CAAGCATGAA AACCGCTTGT TGAGATGAAC TGACAAAGAA ATAATACAAA GTACACACGT 003040
003041 GCTTGTTAGC AAGAGGAAAG AACTATTAGA GTTGGCTGAC TCCAAACAGG AGGAACAAAA TGCCTGCTAA AGTGGGATCG 003120
003121 AACAATGGCT TTGCTCTTTC ATCATGCTCC CTTTCTTCTA GTCTAACTCT AGGACCACCA GCTCTTTCTT CCTCAATTCT 003200
003201 CTTAATTTTC TGTGCTGCTC AGGGGTTTTA ACTGTCTTGG TTAGTATGGG AGACAGACAG ATTTCACAGC GATGAGTGCT 003280
003281 AATCTATCCT AAATGTTAGC AATGAATAAA GCAACCCTAA TGGTAAATGG TATTTAATAA GATCCCTTTT CCCTCAGAAC 003360
003361 AGGCTCTATA TTTAGTGTCT AGAACACAGA AAACTTAAAA ATATTCCACA GAAAGCTAGT GTGATCTGAG AAGAAATAGA 003440
003441 GATTAAATAC TCAGTTAAGG CAATCAGTGT GCCTGTGTCA GCCATAAAGC ACCTCATTTG TATAGTAACA TTTCTTTGGG 003520
003521 GAAACAAAAT CCAGATATAA ATATTAGTAT AAGATCTAAA GATGCAAAAT TCCAATTGAA TGCTAATAAA AGGTATTAAT 003600
003601 AAAACTCTGC TTTAAAGGAC TGACTTCTCA ATGAGTCTGC ACAGCACACT AGAGATTCAA TATGCATATC AAGGTTTTTG 003680
003681 GTTGTTTGTT TTTTTAGTAA CACTGGCATT ATTTATTAAT AATTTAACCA GAAATCTCCC CAAACTTTTA ACTGGAATTT 003760
003761 AAAAAATTAA TTATGGTAAA GTAAGTAAAT TAAAACAAAG AAAAAGTATG AAAGCTATGT TCTAAACTCA CCACATTCAC 003840
003841 CAGCGAGAAT AGATCTGCCC TTCTGGCTAT ATTTGTTACC TACCTATCTC TCTCTCTCTC TCTGTCTCTC TCTCTCCCTC 003920
003921 TCTCTCTCTG TCTCTCTCTT TCCCTCTCTC TCTCTCTCTC TCCGCCCCCC CCACTTCCAC AAGGGATCCA GTCTAGAAAG 004000
004001 AGCATGAACT TAGAAGTCCA GCAGATGTGG GTTCAATTCC TAGTTCTATG GTTTAAAATA CATACACTCA AAAATAAATT 004080
004081 CTCCATTTTC CTGAGCTCTG GTGTTCTCAT CTGGACTTGG GAATAATAGC ACCTCACACA TCAACCTTGT TGAGGATTGC 004160
004161 TTGAGATGAT CATGTAGGGG AGAGGACTCA GGAGAGCCTC TGACAGAGAG ATATGCTTTC AACACAGGCT ATTCATAAGC 004240
004241 ACCCTTCCTA CCTAGTCATC TACTATGTTT TCTCCTCCCC CAGTTTAACT GGTCACCAAG TCTTGCTGAT TTTTCCTTTT 004320
004321 AGTATGTTTC ACTTTCTCTC AGACCCTGCT GATACTGCCT GTCTTCAGAA TCCCCCTCAA TTCTCATCAG GATTGCTGCA 004400
004401 GTAACCACCA AAGTCAATAT TCTGTCTTCA GCCCCAACCT ATCTTAATCC ATCCTCATAA CCCCCAGGGT GATTCTCCTA 004480
004481 AAATATAAAA CTGCCTGAGT TTGACTTTCA GCTATTCTAC TTTATATCTG TATGACTTGG AACAAGTGAC CTGAATTCTC 004560
004561 TCATGCTATA ATTCAAAGCC TATTAACTGG GGATAATAAT TTTCCTACCT CAGTAGGATA TTATATGAAT TAAATAAAGT 004640
004641 CTTGTTCCTC TCCCAAAAAA AAAAAAAAAA A


Labs working on this lncRNA

  • The Department of Gastrointestinal Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, People's Republic of China.

References

  1. 1.0 1.1 1.2 1.3 1.4 Luo Y, Wang C, Yong P, Ye P, Liu Z, Fu Z, Lu F, Xiang W, Tan W, Xiao J. Decreased expression of the long non-coding RNA SLC7A11-AS1 predicts poor prognosis and promotes tumor growth in gastric cancer. Oncotarget. 2017 Nov 7;8(68):112530-112549.