SKAP1-AS1:SKAP1 antisense RNA 1
According to the GO and pathway enrichment analyses, the target genes of RP11-456D7.1 are mainly enriched in the molecular function. In addition, RP11-456D7.1 also positively regulates CCL21, a high-affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and plays a key role in the inflammatory response.
The expression of RP11-456D7.1 is upregulated in the mild and severe pneumonia groups compared with controled groups.
Labs working on this lncRNA
- Department of Hematology, Chinese PLA General Hospital, Beijing, China (mainland).
- Huang S, Feng C, Chen L, Huang Z, Zhou X, Li B, Wang LL, Chen W, Lv FQ, Li TS. Identification of Potential Key Long Non-Coding RNAs and Target Genes Associated with Pneumonia Using Long Non-Coding RNA Sequencing (lncRNA-Seq): A Preliminary Study. Med Sci Monit. 2016 Sep 24;22:3394-3408.