RGMB-AS1

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Annotated Information

Approved Symbol

RGMB-AS1 (RGMB antisense RNA 1)

Disease

non-small cell lung cancer

Chromosome

5q15

Expressions of lncRNA RGMB-AS1 and RGMB mRNA in NSCLC tissues and adjacent normal tissues.[1]
siRNA of lncRNA RGMB-AS1 promoted the expression of RGMB in A549 and SPC-A-1 cells.[1]

RefSeq ID

NR_033932

Ensembl ID

ENSG00000246763

Expression

lncRNA RGMB-AS1 expression is significantly higher in NSCLC tissues than in adjacent normal tissues (P < 0.05).

Experiment Forward primer Reverse primer
qRT–PCR 5'-AGTGGGCAAACTTCAACGTTC-3’ 5'-GAGCTGCCATTGAATTAATCCG-3’[1]

Function

Knockdown RGMB-AS1 promotes the expression of RGMB in A549 and SPC-A-1 cells.[1]

Labs working on this lncRNA

  • Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. [1]

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Li P, Li J, Yang R, Zhang F, Wang H, Chu H, Lu Y, Dun S, Wang Y, Zang W, Du Y, Chen X, Zhao G, Zhang G. Study on expression of lncRNA RGMB-AS1 and repulsive guidance molecule b in non-small cell lung cancer. Diagn Pathol. 2015 Jun 9;10:63. doi: 10.1186/s13000-015-0297-x.

Sequence

>gi|299890848|ref|NR_033932.1| Homo sapiens RGMB antisense RNA 1 (RGMB-AS1), long non-coding RNA

000001 CAAGCTCGGG GCGGTGTTGG AAATCTGAAT GTCACCCGCG GTCCGGAGCA GATAGGATGG GCTGGGAAGG TACCCGCGAA 000080
000081 CTGCCGCCGG AATTCGCTGG CAGCTGTGCG AGGCTCAGGT GTTCTAGTTT GACATTTCCC TTCCTGAAAG CGGCAAGGAG 000160
000161 AGGTCTAAGA GTGGGCAAAC TTCAACGTTC GGTTACAGTG TAATTAATGA GAGTGGTGGG TTTTTATGCA GTGTAATTAT 000240
000241 GCCACGATTT GTTGTTGCTC AGTGGCTTTT TCACAAATTT CTACAGATTA TTTAAATTTT CCACAAATTT CTACGGATTA 000320
000321 ATTCAATGGC AGCTCACTTT CTCCTTTTAT GATCGGATGG GTCCGAAAGT GAGGAAAAAG ACAATTGTCT ACAAAGAAAG 000400
000401 AGGCTGCCAA GTGGAGACAG AAAAGCAGTT ATGAGACTGA TGATAGATTC CAATTTGTTA TCGAAAGGAA GGAGGAGACC 000480
000481 TGAACAGTAC ATCCGGAGAA TCCAGCAAAG CATACTACGG CATGAACGTG CAAGTGGACA GAATTAAAAC ACATGCCAGA 000560
000561 AACACTAATG GATTCTAAAC AAGATGCAGT TTCATTTCCT GAGCCTATAC GTGATGTTTT TAACTGTTCT CCAGTTAATA 000640
000641 TGTCTCCATT TCCAGAAATC TAACAGGAGA ATCTCTGACT GCTTAACAGA TCACCTAAGC TTGCGATTTG TGCAATCCTT 000720
000721 TCTAGAGTAA GGGCTCCCCG GCTGCTCCCC GGCCACTGTG TACCCAAAGC AGCGGCTGAA ATAGCCCGGA GTCCAACAGC 000800
000801 TCAGCGTCAA GCAGCTCGTG GTTTGTACTT ACATCATTTT TTTTTTCAGA GCAAGAGTGA AAGTTTATTA AAAAGCGTTA 000880
000881 GAACAGTAAG GAAAGGAAAG GAGAGAAAAT AAGGAAAGTA CAACTTGGAA GAGGGCCAAG CGGGCGACTT GAGAAATCAA 000960
000961 GTGCCTGTAC TTACATCATT CTTAACCCTT TCGCTCCTGG AGGGGGCTCA GCGGGATCAG GGGGCCCCTG AACTTCGGAA 001040
001041 CACGCAGGAC CTGGGTGTGA GAGAAGAGTC CCAAAGCTTG GCGTGAGCAA TGCACTCGCG GAGGGAGAGA GCCCGGGGCT 001120
001121 TGCGGGGGGC TCATCACCCG CTCGTAGACA ACGGGCCCCC GCAATCCCTG CGGGCTCCGC CGCTGCTCTC ACCGCTCAAA 001200
001201 ACGGCAGGTG CAAAAAGCAT TTGGGAGCCG CTTGCCAGCG CGCGGAGGTA ATGCGCTTCC TGTCCATTTA TCTCAGGAAA 001280
001281 CCAGTGCAGC CTTCCCTTCG AAACAAAATT AACCTCTCAT TAGCCAGCCA CTCGCTCCCA AGAAGGCCTT AAAAGCTTTA 001360
001361 CCAGCTCGCT AATGTATTTA GGCTTTTCTT CCAGGCAAAC GCAGCCGCCG GTCTTGACTG CCATCGCCCA AGGGGTTCCT 001440
001441 CTGGGCTCTC CCGCGAGCCA ACAGCCGACC TCTCTCCAGC CTAGTCTGGG AAACTCCAGC CAACCCAGGA TCCCATTTTG 001520
001521 TAGTCCCGGG CAGACCCGAA ACCCCTGAAA GAACTCCACT CCAGAAGACG CCAGAACAAG TTCCCACGAA TTTCATGGGC 001600
001601 GCCCTTCACA TGAAAACCTC AGCTCCCCTA TCCTCAAGGA ACGGGGAAGG GCGCCGGGGA GGGACTTCGG TGGCCAGCTG 001680
001681 TCCCTGGGTC GTGGGCGCTG TTTGCTCTGC GGAGCGCCAG CCCTGCACAC AGCGGGTGCG GGAAGCGTTG ATGGGAGGCT 001760
001761 GGAGGGCGGG GTGAGCGTAA ACTAGGATCT AGCCGGTTCC AGGCGTGGAG AATCAAATGT GGTCCTAGAT CTGTAAGTTG 001840
001841 CGAAAAGGGG CTTTTGGGAG CGTCAGAGCT TTCTCACTCC GGTCCCCCGC CGCCTTGAGG CTGGCAGATT TATACCACAC 001920
001921 AGGTGGATGG AGACCTAAAC AAAACAGTCC CGGCCGCTGC CTGCCGCTCG CCCCCCACGT CCCCCGGGCC CACCGCAAAC 002000
002001 TTCAACAAAA TAAACAACTC ACCACAGGCA AAAAAAAAAA AAAAAAAAAA AAA
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