NEXN-AS1

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Annotated Information

Approved Symbol

NEXN-AS1 (NEXN antisense RNA 1)

Previous Symbols

C1orf118

Synonyms

FLJ90637

Chromosome

1p31.1

RefSeq(supplied by NCBI)

NR_103535

pubmed IDs

27713484

Characteristics

There is a risk SNP rs114020893 in the lncRNA NEXN-AS1 region at 1p31.1.[1]

Function

The SNP rs114020893 may change the folding structure of the NEXN-AS1 and contribute to lung cancer susceptibility.[1]

Labs working on this lncRNA

  • Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University; Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China.[1]

References

  1. 1.0 1.1 1.2 1: Yuan H, Liu H, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, McLaughlin J, Brhane Y, Brennan P, Bickeboeller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, Heinrich J, Risch A, Christiani DC, Gümüş ZH, Klein RJ, Amos CI, Wei Q. A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer. Sci Rep. 2016 Oct 7;6:34234. doi: 10.1038/srep34234.