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Revision as of 07:28, 20 February 2014


Welcome to LncRNAWiki
52,619 human long non-coding RNAs inside
Introduction
lncRNAWiki is a wiki-based database for management of human lncRNAs, aiming to harness collective intelligence to collect, edit, and annotate information about human lncRNAs. This database is a publicly editable and open-content platform for community curation of human lncRNAs, bearing the potential to become a comprehensive and up-to-date knowledge base for human lncRNAs.
Data sources
Here we integrate human lncRNA sequences from GENCODE, NONCODE, LNCipedia, and lncRNAdb, and obtain ~53,000 non-redundant lncRNA transcripts.
Data source.jpg

Note: Purple indicates LncRNAdb.
Classification

We previously summarized classification methods of lncRNAs according to their four major features (namely, genomic location and context, effect exerted on DNA sequences, mechanism of functioning, and their targeting mechanism), explored potential relationships between different classification categories, and generalized and compared biological features of different lncRNAs within each category (Ma etal. 2013, RNA Biology).
Here, we classify these lncRNAs into 9 groups based on their genomic location.

Classfication.jpg
Publications
About Us
Our group works in the field of Computational Biology and Bioinformatics (CBB), currently with a particular focus on building biological knowledge wikis in aid of community curation of massive biological knowledge.
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