|
|
| Line 1: |
Line 1: |
| − | ==Annotation== | + | ==Annotated Information== |
| − | ===Name=== | + | ===Name=== |
| − | Approved symbol: LINC00319 | + | Approved symbol： LINC02885 |
| − | | + | |
| − | Approved name: long intergenic non-protein coding RNA 319 | + | Approved name： long intergenic non-protein coding RNA 2885 |
| − | | + | |
| − | HGNC ID: HGNC:19730 | + | HGNC ID： HGNC:41188 |
| − | | + | |
| − | Previous symbols: C21orf125; NCRNA00319 | + | Previous symbols： ISX-AS1 |
| − | | + | |
| − | Previous names: chromosome 21 open reading frame 125; non-protein coding RNA 319 | + | Previous names： ISX antisense RNA 1 |
| − | | + | |
| − | Alias symbols: PRED49; FLJ38036
| + | RefSeq ID： NR_138042 |
| − | | |
| − | RefSeq ID: NR_026960 | |
| − | | |
| − | LncBook ID: [https://bigd.big.ac.cn/lncbook/transcript?transid=HSALNT0289323 HSALNT0289323]
| |
| − | | |
| − | ===Characteristics ===
| |
| − | [[File:Functional domains of 7SK RNA..png|right|thumb|Functional domains of 7SK RNA([https://www.ncbi.nlm.nih.gov/pubmed/19246988 (Diribarne 2009)])]]
| |
| − | | |
| − | ===Expression===
| |
| − | LINC00319 is up-regulated in human primary lung adenocarcinoma tissues<ref name="ref1" />.
| |
| − | | |
| − | ===Regulation===
| |
| − | | |
| − | ===Function===
| |
| − | [[File:Model of hLarp7 recognition of the 7SK.png|right|thumb|Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP([https://www.ncbi.nlm.nih.gov/pubmed/29946027 (Eichhorn 2018)])]]
| |
| − | | |
| − | Linc00319 promotes cell proliferation and invasion in lung cancer cells by directly binding with and downregulating the tumor suppressor miR-32.<ref name="ref1" />
| |
| − | | |
| − | ===Disease===
| |
| − | lung cancer <ref name="ref1" />
| |
| − | | |
| − | lung adenocarcinoma carcinogenesis <ref name="ref2" />
| |
| − | | |
| − | ===Evolution===
| |
| − | Please input evolution information here.
| |
| − | | |
| − | ==Labs working on this lncRNA==
| |
| − | * College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China.<ref name="ref1" />
| |
| − | * Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, China.<ref name="ref2" />
| |
| − | | |
| − | ==References==
| |
| − | <references>
| |
| − | <ref name="ref1"> Zhou B, Yuan W and Li X. Long Intergenic Noncoding RNA 319 (linc00319) Promotes Cell Proliferation and Invasion in Lung Cancer Cells by Directly Downregulating the Tumor Suppressor MiR-32[J]. Oncol Res, 2017.
| |
| − | </ref>(1)
| |
| − | <ref name="ref2">Zhang ZW, Chen JJ, Xia SH, et al. Long intergenic non-protein coding RNA 319 aggravates lung adenocarcinoma carcinogenesis by modulating miR-450b-5p/EZH2[J]. Gene, 2018, 650: 60-67.</ref>(2)
| |
| − | </references>
| |
Annotated Information
Name
Approved symbol： LINC02885
Approved name： long intergenic non-protein coding RNA 2885
HGNC ID： HGNC:41188
Previous symbols： ISX-AS1
Previous names： ISX antisense RNA 1
RefSeq ID： NR_138042
