Difference between revisions of "Main Page"

Revision as of 09:23, 15 January 2020

Welcome to LncRNAWiki

106,063 human long non-coding RNAs inside

Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

LncRNAWiki, an important component of LncBook, provides community annotations of human lncRNAs

Featured lncRNAs

Top 10 lncRNA-associated diseases

Diseases and their associated lncRNAs' counts are listed below.

Neoplasms: 1,077

Digestive System Diseases: 427

Male Urogenital Diseases: 117

Female Urogenital Diseases and Pregnancy Complications: 196

Respiratory Tract Diseases: 224

Skin and Connective Tissue Diseases: 165

Endocrine System Diseases: 129

Cardiovascular Diseases: 155

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 150

Nervous System Diseases: 103

Extensively curated

HOTAIR

MALAT-1

H19

MEG3

NEAT1

PVT1

GAS5

CDKN2B-AS1

HOTTIP

7SK

BANCR

BTG3-AS1

CERNA2

FLICR

GUARDIN

LINC-ROR

PINCR

PLUT

LUNAR1

SRA

KCNQ1OT1

PCGEM1

XIST

BCYRN1

TUG1

UCA1

HULC

PRNCR1

TP53COR1

PANDAR

Function

Functional mechanisms and their associated lncRNAs' counts are listed below.

How to Cite

If you use any data or information in your work, please cite the following publications.

Primary publication:

LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs. (2015) Nucleic Acids Research, 43:D187-92.

Related publication:

Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook. Curr Protoc Bioinformatics 2019.

Visitor Statistics

@@ Line 2: / Line 2: @@
 __NOTOC__
 __NOEDITSECTION__
 <!-----------------title--------------------->
 {|style="width:100%; margin-top:10px; background-color:#f6f6f6; border:1px solid #d2d2d2; margin-bottom: 10px;"
 |style="width:50%; text-align:center; white-space:nowrap; color:#000"|
 <div style="font-size:180%; border:none; margin:0; padding:.5em; color:#000;">Welcome to LncRNAWiki</div>
-<div style="padding:0em; font-size:100%">[http://bigd.big.ac.cn/lncbook/lncrnas 290,405] human long non-coding RNAs inside</div>
+<div style="padding:0em; font-size:100%">[[:Category:Transcripts|106,063]] human long non-coding RNAs inside</div>
 |style="width:18%;|
-*[http://bigd.big.ac.cn/lncbook/lncrnas Transcripts]
+*[[:Category:Transcripts|Transcripts]]
-*[http://bigd.big.ac.cn/lncbook/featuredlncrna Featured LncRNAs]
+*[[:Category:Genes|Genes]]
+*[[LncRNAWiki:Classification|Classification]]
 |style="width:18%;|
-*[http://bigd.big.ac.cn/lncbook/diseases Disease]
+*[[LncRNAWiki:Featured|Featured LncRNAs]]
+*[http://bigd.big.ac.cn/lncbook/disease Disease]
 *[http://bigd.big.ac.cn/lncbook/function Function]
 |style="width:18%;|
+*[[LncRNAWiki:Small_proteins|Small Proteins]]
 *[http://bigd.big.ac.cn/lgc Prediction]
 *[http://bigd.big.ac.cn/lncbook/blast BLAST]
 |}
 <!---------------welcome Box----------------->
 {|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
@@ Line 25: / Line 28: @@
 <div style="padding:1em 0.5em;">
 {{LncRNAWiki:Summary}}
-<div style="padding:0.2em 0.5em;text-align:center;font-weight:bold;color:#2d2d2d;">'' LncRNAWiki, an import component of '' [http:/bigd.big.ac.cn/lncbook LncBook], ''provides community annotations of human lncRNAs''</div>
+<div style="padding:0.2em 0.5em;text-align:center;color:#2d2d2d;"> ''LncRNAWiki, an important component of '' [http://bigd.big.ac.cn/lncbook '''LncBook'''], ''provides community annotations of human lncRNAs''</div>
 </div>
 |}
@@ Line 32: / Line 35: @@
 {|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
 |-
+<!-----------Featured lncRNAs------------>
+|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
+<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://lncrna.big.ac.cn/index.php/LncRNAWiki:Featured Featured lncRNAs]</div>
+<div style="padding:0.5em 0.5em;">[[File:Featured-2019-3.png|center|500px|link=LncRNAWiki:Featured]]</div>
+|style="padding:0px 4px;"|
 <!-----------Top 10 lncRNA-associated diseases------------>
-|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:45%;"|
+|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
-<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [[LncRNAWiki:Disease|lncRNA-associated diseases]]</div>
+<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Top 10  [http://bigd.big.ac.cn/lncbook/disease lncRNA-associated diseases]</div>
 <div style="padding:0.5em 0.5em;">
 ''Diseases and their associated lncRNAs' counts are listed below.''
-* [[LncRNAWiki:Cancer|Cancer]]: 212
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Neoplasms Neoplasms]: 1,077
-* [[LncRNAWiki:Nervous System Diseases|Nervous System Diseases]]: 37
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Digestive%20System%20Diseases Digestive System Diseases]: 427
-* [[LncRNAWiki:Cardiovascular Diseases|Cardiovascular Diseases]]: 22
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Male%20Urogenital%20Diseases Male Urogenital Diseases]: 117
-* [[LncRNAWiki:Congenital, Hereditary, and Neonatal Diseases and Abnormalities|Congenital, Hereditary, and Neonatal Diseases and Abnormalities]]: 21
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Female%20Urogenital%20Diseases%20and%20Pregnancy%20Complications Female Urogenital Diseases and Pregnancy Complications]: 196
-* [[LncRNAWiki:Musculoskeletal Diseases|Musculoskeletal Diseases]]: 20
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Respiratory%20Tract%20Diseases Respiratory Tract Diseases]: 224
-* [[LncRNAWiki:Hemic and Lymphatic Diseases|Hemic and Lymphatic Diseases]]: 19
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Skin%20and%20Connective%20Tissue%20Diseases Skin and Connective Tissue Diseases]: 165
-* [[LncRNAWiki:Endocrine System Diseases|Endocrine System Diseases]]: 18
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Endocrine%20System%20Diseases Endocrine System Diseases]: 129
-* [[LncRNAWiki:Mental Disorders|Mental Disorders]]: 14
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Cardiovascular%20Diseases Cardiovascular Diseases]: 155
-* [[LncRNAWiki:Skin and Connective Tissue Diseases|Skin and Connective Tissue Diseases]]: 9
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Congenital,%20Hereditary,%20and%20Neonatal%20Diseases%20and%20Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities]: 150
-* [[LncRNAWiki:Nutritional and Metabolic Diseases|Nutritional and Metabolic Diseases]]: 9
+* [http://bigd.big.ac.cn/lncbook/disease?filter=diseasemesh&term=Nervous%20System%20Diseases Nervous System Diseases]: 103
 </div>
+|}
+<!--------------main part two---------------->
+{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
+|-
+<!-----------------Extensively curated---------------------->
+|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:50%;"|
+{|style="width:100%;"
+<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Extensively curated</div>
+|style="width:33%;|
+* [[NONHSAT028508|''HOTAIR'']]
+* [[ENST00000534336.1|''MALAT-1'']]
+* [[NONHSAT017465|''H19'']]
+* [[NONHSAT039745|''MEG3'']]
+* [[ENST00000501122.2|''NEAT1'']]
+* [[ENST00000513868.2|''PVT1'']]
+* [[NONHSAT007663|''GAS5'']]
-|style="padding:0px 4px;"|
+* [[Lnc-C9orf53-2:1|''CDKN2B-AS1'']]
+* [[NONHSAT119717|''HOTTIP'']]
-<!-----------Featured lncRNAs------------>
+* [[NONHSAT113149|''7SK'']]
-|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:54.5%;"|
-<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Featured|Featured lncRNAs]]</div>
-<div style="padding:0.5em 0.5em;">
-<table>
-<tr>
-<td>[[File:Featured4.png|left|430px|link=LncRNAWiki:Featured]]</td>
-<td valign="top">
-Extensively curated:
+|style="width:33%;|
 * [[BANCR|''BANCR'']]
@@ Line 82: / Line 112: @@
 * [[FLICR|''FLICR'']]
-* [[JADRR|''JADRR'']]
+* [[GUARDIN|''GUARDIN'']]
 * [[LINC-ROR|''LINC-ROR'']]
@@ Line 90: / Line 120: @@
 * [[PLUT|''PLUT'']]
-* [[SMILR|''SMILR'']]
+* [[LUNAR1|''LUNAR1'']]
+* [[Lnc-SRA1-1:1|''SRA'']]
+|style="width:34%;|
+* [[NONHSAT017524|''KCNQ1OT1'']]
+* [[NONHSAT076153|''PCGEM1'']]
+* [[NONHSAT137541|''XIST'']]
+* [[Lnc-EPCAM-1:2|''BCYRN1'']]
+* [[NONHSAT084827|''TUG1'']]
+* [[Lnc-OR10H5-1:1|''UCA1'']]
-* [[LUNAR1|''LUNAR1'']]
+* [[NONHSAT107640|''HULC'']]
-* [[XACT|''XACT'']]
+* [[NONHSAT129019|''PRNCR1'']]
+* [[TP53COR1|''TP53COR1'']]
-</td>
+* [[Lnc-CDKN1A-1:1|''PANDAR'']]
-</tr>
-</table>
-</div>
 |}
-<!--------------main part two---------------->
+|style="padding:0px 4px;"|
-{|border="0" cellspacing="0" cellpadding="0" style="margin:1em 0; background:transparent; width:100%;"
-|-
-<!-----------------Small proteins---------------------->
-|valign="top" style="border:1px solid #66B3FF; background-color:transparent;45%;"|
-<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Small_proteins|Small proteins]]</div>
-<div style="padding:0.5em 0.5em;">[[File:SmallPRO-5.png|center|220px|link=LncRNAWiki:Small_proteins]]</div>
-* [[LncRNAWiki:Small_proteins|'''9,387''']] lncRNAs potentially encoding small proteins
-* '''2,246''' small proteins identified with high confidence, by considering protein instability, secondary structure and transmembrane helix
+<!-----------------Function---------------------->
+|valign="top" style="border:1px solid #66B3FF; background-color:transparent;"|
+<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[http://bigd.big.ac.cn/lncbook/function Function]</div>
-|style="padding:0px 4px;"|
+<div style="padding:0.5em 0.5em;">
+''Functional mechanisms and their associated lncRNAs' counts are listed below.''
-<!-----------------Classification---------------------->
+* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=transcriptional%20regulation Transcriptional regulation]: 282
+* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=ceRNA ceRNA]: 73
+* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=translational%20control Translational control]: 13
+* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=protein%20localization Protein localization]: 6
+* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=splicing%20regulation Splicing regulation]: 4
+* [http://bigd.big.ac.cn/lncbook/function?filter=functionmec&term=RNAi RNAi]: 3
-|valign="top" style="border:1px solid #66B3FF; background-color:transparent;width:54.5%;"|
+</div>
-<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">[[LncRNAWiki:Classification|Classification]]</div>
-<div style="padding:0.5em 0.5em;">[[File:Classification.png|center|400px|link=LncRNAWiki:Classification]]</div>
 |}
@@ Line 134: / Line 176: @@
 * [http://nar.oxfordjournals.org/content/early/2014/11/15/nar.gku1167.full '''LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs'''.] (2015) ''Nucleic Acids Research'', 43:D187-92.
-Related publications:
+Related publication:
-* [https://www.ncbi.nlm.nih.gov/pubmed/29036542 '''Database Resources of the BIG Data Center in 2018'''.] ''Nucleic Acids Research 2018''.
+* [https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpbi.82 '''Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook'''.] '' Curr Protoc Bioinformatics 2019''.
-* [http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1060.full '''The BIG Data Center: from deposition to integration to translation'''.] (2017) ''Nucleic Acids Research'', 45:D18-24.
-* [https://www.landesbioscience.com/journals/rnabiology/article/24604/?nocache=227993923 '''On the classification of long non-coding RNAs'''.] (2013) ''RNA Biology'', 10:924-933.
 </div>

Difference between revisions of "Main Page"

Revision as of 09:23, 15 January 2020

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