LINP1 (lncRNA in non-homologous end joining pathway 10
Compared with the non-basal lines, LINP1 has significantly higher expression level. 
LINP1 serves as a modular scaffold and uses different regions to interact with the two proteins Ku80 and DNA-PKcs which participate in the NHEJ pathway.  Suppressing LINP1 expression can impair DNA repair activity in vivo, which in turn sensitizes tumors to IR treatment.
LINP1 is activated by the EGF (RAS-MEK-JNK) pathway and repressed by the p53 signaling pathway. 
Labs working on this lncRNA
- Center for Research on Reproduction &Women's Health, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
- Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
- Zhang, Y., et al., Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. Nat Struct Mol Biol, 2016. 23(6): p. 522-30.