Difference between revisions of "LINC02593"

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Latest revision as of 06:10, 24 December 2018

LINC02593, long intergenic non-protein coding RNA 2593, potentially serves as novel candidate biomarkers for the identification of BC patients at high risk for tumor recurrence.

Annotated Information

Name

LINC02593: long intergenic non-protein coding RNA 2593 (HGNC:53933)

Alias

AL645608.1 (HGNC:53933)

Characteristics

LINC02593 is a long non-protein coding gene located at chromosome 1p36.33. It is one of the five-lncRNA signature that was studied to be involved in breast cancer metastasis-related pathways. [1]

Function

It may be implicated in breast cancer pathogenesis. [1] It is related to EMT in hepatocellular carcinoma HCC. [2]

Regulation

Please input information here.

Expression

This lncRNA is differentially expressed in hepatocellular carcinoma (HCC). [2]

Disease

  • Breast cancer [1]
  • Hepatocellular carcinoma [2]

Labs working on this lncRNA

  • College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China.
  • Division of Biostatistics, Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL.
  • University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, Miami, FL.
  • Key Laboratory of Cardiovascular Medicine Research, Harbin Medical University, Ministry of Education, China.
  • Department of Pharmacy, Linyi People's Hospital, Linyi, 276400, Shandong Province, China
  • Department of Obstetrics and Gynecology, Linyi People's Hospital, Linyi, 276400, Shandong Province, China

References

  1. 1.0 1.1 1.2 Li J, Wang W, Xia P, Wan L, Zhang L, Yu L et al. Identification of a five-lncRNA signature for predicting the risk of tumor recurrence in patients with breast cancer[J]. International journal of cancer. 2018, 143(9):2150-2160.
  2. 2.0 2.1 2.2 Zhang Z, Wang S & Liu W. EMT-related long non-coding RNA in hepatocellular carcinoma: A study with TCGA database[J]. Biochemical and biophysical research communications. 2018, 503(3):1530-1536.

Sequence

>gi|100130417|ref|NR_026874.2| Homo sapiens long intergenic non-protein coding RNA 2593 (LINC02593), transcript variant 1, long non-coding RNA

000001 CCGAGTGCAG AGCCAGGGCC CAGCACGAAG GCCTTGGGCT CCAGTCCGTG TGCCCCACAT CCCTACATGA GTGAGGGTGG 000080
000081 AGGGATGGTG CCTCTGCCAC GGCCACGGTG CCGCCGTCCA CGTCAGCTCA CTCTCAGCAC AGGTGCTGTG TGACGGCCTC 000160
000161 GGGCCACACC GCTTGTTCTG AGGCCCCTAG CAGGTCGGGC TTGTGCTGGC TGCACATTGG CTGGTGAGCT TGGCGGGTCT 000240
000241 GTGGGCACGG AGAGACCAGA ACGTGCGTAA CAGGCCCGAT GAGGGTGCCA GGCTGTGGCG ACCCCCGAGC TTCAGAGGAG 000320
000321 AGGGGCACCA GCCGGGGGCC CTGCACAGGC AGCCTCAGAG AGAGGAAAGC TCACGATCTG GGAGAACTCC AGGCCTGGCC 000400
000401 CAGTGAAGAC GTCCTTATCT TCAGCAGACA TTGCCCAGTG CAAGGGGAGG GATTTTTAGG GCGGCAAGCT CAGGTGGACA 000480
000481 GGCAGTTTTA TTCTGTTTCC CATGTCAAGT CCAGCCCCAG ACTGACTTTC TGAGGTCACA GACGGAGCCT CACCCCATCC 000560
000561 AAGGCGGTGT CCTGGACTCC CACTGTGCTC CCCAGAGGGC AGGGTACCTG GGGCCCAGCC CGGGCGGCAG GAGGGACTCA 000640
000641 GCCCCTCGCC CAGGCAGGAA GGGTCCCAAG CAGAGGCCCC TCCCTCAGGC ACTCCCCAGC CCACACCTGC AGCACTGGGA 000720
000721 CCAAGACTAA TAAAACACCA GCCTCACGGA AGACAGCTTT ATCTTGTTGA TCGGAAGTCT GCCAGCCCAA TTTATGATGG 000800
000801 AACATAAGAT CTCTAAATCT GAATTTACGC TCTGTAGCGT AACGAGAGGT CAATAAGATT AAACGGGGGC TCAGGAGAGG 000880
000881 ACCAGCGTCA GGCTCACTGC GAGGTGCTGC ACAGAAAACC CACAGCCAGA GCCCCTGGGC CCAGCCCAGG CAAGACCAGA 000960
000961 AAAGGAGGGG GCAGGTGGGA GACCAGCCTG GGGCTCCCGG GAAGCCCACG GGATGGAGGC GGGAGAGCCA GGAGGCCTGG 001040
001041 GGCAACCCTG GGACGGTTCC TGGATCGAGG AGAGCAGGGG GGTGATGAGG GTTCCCTCAG GGCTGGGGAG CCTTCTCCTG 001120
001121 GTCTCAGACC CACCCCCCTT CAGCTCCCAA GCCCTGGGTG CCCCTGGCTC TGAGGACAGT TGGGAATCTT CCCTGAGGCA 001200
001201 GGTTCAAGGA CAGAGCTCTG ACCCTGGCCC AGGGCTGCTT TGGGTGCCTA TGAACTCGGC TTCTGGCTCA GAGCAGTTCC 001280
001281 CTGCACCCCT TCCTGAGCCC TCTGTCCTCT GGAACCCGTG GGCAGGGTGA GGGACGGGTG TTCCTTCTGG GTGGGGGCCT 001360
001361 GGGCGCCCAG CCAGCACGAC GCTGGCTTGC TGAGCTTAGG GCAGACCCCG ACTTCAGAAT TTATACAAAT AAATGCAATG 001440
001441 AAAAGTGCTG GCAACCTGAT CTGATTACAG AGTCATTCAT TCTCTGGTCG TTAATAATTT GTGCAA