LINC02231

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Annotated Information

Name

LINC02231:long intergenic non-protein coding RNA 2231

RP11-766N7.4 [1]

Characteristics

Long noncoding RNA RP11-766N7.4 is located on the reversed strand in 12q14.3 region with a length of 447 bps [1].

Function

RP11-766N7.4 expression is negatively correlated with lymph node metastasis and tumor stage, and RP11-766N7.4 inhibites cellular migration and invasion by suppressing EMT (Epithelial-Mesenchymal Transition) process [1].

Expression

RP11-766N7.4 is remarkably down-regulated in Esophageal squamous cell carcinoma(ESCC) tissue samples compared with the paired adjacent tissues [1].

Diseases

Esophageal squamous cell carcinoma [1]

Labs working on this lncRNA

  • Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China.

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Yao GL, Pan CF, Xu H, Wei K, Liu B, Zhai R, Chen YJ. Long noncoding RNA RP11-766N7.4 functions as a tumor suppressor by regulating epithelial-mesenchymal transition in esophageal squamous cell carcinoma. Biomed Pharmacother. 2017 Apr;88:778-785.
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