LINC01426

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Annotation

Name

LINC01426

Alias

NA

Disease

Disease: esophageal squamous cell cancer (PMID:25486427)

Dysfunction type: expression

Description: LincRNA-uc002yug.2 was commonly overexpressed in ESCC. Moreover, lincRNA-uc002yug.2 promoted a combination of RUNX1 and alternative splicing (AS) factors in the nucleus to produce more RUNX1a, the short isoform and inhibitor of RUNX1, and reduce CEBPa (CCAAT/enhancer-binding protein-a) gene expression, thereby promoting ESCC progression. The expression levels of lincRNA-uc002yug.2 in ESCC might be a prognostic factor for survival.


Function

Function Mechanism: NA (PMID:25486427)

Biological Process: pathogenic process

Description: NA