Difference between revisions of "LINC01138"

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==Annotated Information==
 
==Annotated Information==
 
===Approved Symbol===
 
===Approved Symbol===
LINC01138
+
LINC01138C (long intergenic non-protein coding RNA 1138)
===Approved Name===
 
long intergenic non-protein coding RNA 1138
 
 
===Previous Symbols===
 
===Previous Symbols===
 
LINC00875
 
LINC00875
Line 10: Line 8:
 
===Chromosome===
 
===Chromosome===
 
1q21.2
 
1q21.2
===RefSeq ID===
 
NR_027468
 
===OMIM ID===
 
_
 
 
===RefSeq(supplied by NCBI)===
 
===RefSeq(supplied by NCBI)===
 
NR_027468
 
NR_027468
Line 20: Line 14:
 
===Disease===
 
===Disease===
 
prostate cancer
 
prostate cancer
 +
===Expression===
 +
The expression level of LINC01138 is markedly increased in invasive extraprostatic tumors (pT3a, pT3b and T4 stages) as compared with intraprostatic localized tumors (pT2a , pT2b and pT2c stages).<ref name="ref1" />
 +
 +
===Function===
 +
The high level of LINC01138 is correlated with a short biochemical recurrence-free survival times.<ref name="ref1" />
 +
LINC01138 promotes the proliferation and inhibited apoptosis of PCa.<ref name="ref1" />
 +
LINC01138 functions as an oncogenes in prostate cancer.<ref name="ref1" />
 +
 +
==Labs working on this lncRNA==
 +
* State Key Laboratory of Genetic Engineering, Shanghai Engineering Research Center Of Industrial Microorganisms, School of Life Science, Fudan University, Shanghai 200433, PR China.
 +
 +
==References==
 +
<references>
 +
<ref name="ref1">Wan, X., et al., Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer. Oncotarget, 2016. 7(37): p. 60503-60518.
 +
</ref>(1)
 +
</references>

Revision as of 14:19, 13 November 2017

Annotated Information

Approved Symbol

LINC01138C (long intergenic non-protein coding RNA 1138)

Previous Symbols

LINC00875

Synonyms

FLJ39739

Chromosome

1q21.2

RefSeq(supplied by NCBI)

NR_027468

pubmed IDs

27556357

Disease

prostate cancer

Expression

The expression level of LINC01138 is markedly increased in invasive extraprostatic tumors (pT3a, pT3b and T4 stages) as compared with intraprostatic localized tumors (pT2a , pT2b and pT2c stages).[1]

Function

The high level of LINC01138 is correlated with a short biochemical recurrence-free survival times.[1] LINC01138 promotes the proliferation and inhibited apoptosis of PCa.[1] LINC01138 functions as an oncogenes in prostate cancer.[1]

Labs working on this lncRNA

  • State Key Laboratory of Genetic Engineering, Shanghai Engineering Research Center Of Industrial Microorganisms, School of Life Science, Fudan University, Shanghai 200433, PR China.

References

  1. 1.0 1.1 1.2 1.3 Wan, X., et al., Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer. Oncotarget, 2016. 7(37): p. 60503-60518.