Difference between revisions of "LINC00888"

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===Name===
 
===Name===
 
LINC00888:long intergenic non-protein coding RNA 888
 
LINC00888:long intergenic non-protein coding RNA 888
 
===Characteristics===
 
LINC00888, which is located on chromosome 3, has the most co-expressed mRNAs among the upregulated lncRNAs in the three comparisons (primary melanoma versus normal skin, metastatic melanoma versus normal skin, and metastatic melanoma versus primary melanoma). <ref name="ref1" />
 
  
 
===Function===
 
===Function===
LINC00888 is negatively correlated with BNC1, which implies a potentially active role in melanoma. <ref name="ref1" />
+
LINC00888 is negatively correlated with BNC1 in melanoma, which implies a potentially active role of LINC00888 in tumor development <ref name="ref1" />.
  
 
===Diseases===
 
===Diseases===
Melanoma<ref name="ref1" />
+
Melanoma <ref name="ref1" />
 +
 
 
===Expression===
 
===Expression===
LINC00888 is an upregulated lncRNA in PM and MM.<ref name="ref1" />
+
LINC00888 is upregulated in primary melanoma and metastatic melanoma <ref name="ref1" />.
  
 
===Sequence===
 
===Sequence===

Latest revision as of 07:24, 31 August 2017

Annotated Information

Name

LINC00888:long intergenic non-protein coding RNA 888

Function

LINC00888 is negatively correlated with BNC1 in melanoma, which implies a potentially active role of LINC00888 in tumor development [1].

Diseases

Melanoma [1]

Expression

LINC00888 is upregulated in primary melanoma and metastatic melanoma [1].

Sequence

>NR_038301.1 Homo sapiens long intergenic non-protein coding RNA 888 (LINC00888), transcript variant 1, long non-coding RNA

000001 ACTTCACCAA GCGGCCGGTC CGAGGGGACA TGGCGGCAAC CTCTGCAGCG TCAGTGCTGC TGGCGGGTGC AAGAAACTGG 000080
000081 TGGCGACACT GCCTGAGCCC GCTGCTGTTG CCAAGGTGAC GAGGCATAAA GCCGCGGTGG ATCGGTGCGT GGGGGCGCGG 000160
000161 GGTGGGTGGT GAAGGGAGAA CGAAGCTCGA GCGGAAAGAC AGGACCGCGA CCGCTTGTCA GGGGATTCGG CTTCCAGTCC 000240
000241 CCCTTCCAGA GGGCGTCCTT CTGCAGCCAG GCCTCTGTCT TCCCCCGCCC CCACACGAGT CTCACTTCAT CACCATGCTG 000320
000321 GAGTGCAGTG GCACTATCTG AGATCACTGC AATCTCCGCC TCTCGGATTC AAGCGATTCT CGTGCCTCAG CCTCCCGAGT 000400
000401 AGTAGCTGGG AGTACAGGCA TGTGCCACCA TGCCCAGCTA ATTTTTGTAT TTTTGGTACA GACCTGGTTT CGCCTTGTTG 000480
000481 GCCAGGCTGG TCTCGAGCTT CTGACCTCAA GTGATCCGCC TGCCTCGGCC TTCCAAAGTG CTGGGATTAC AGGCGTGAAC 000560
000561 CACTGAGACT GGTCAGTTAT TGGCTCTTTT TAAAGATTGT GTTGCTTTCT GCCTCAATAT TAATATGTTG GAAGTTACCA 000640
000641 AGAAGTTCAT GACAGATCTA TTTCAAATTC TGGTGAAGAA GGAAGAATTG GCCCTTGAAA GAATCAGTGT TTTACAATAA 000720
000721 TTTTGAAAGA GGGTAGCGAC AGAAGGAAGA AAACATTATC AGGAGGGAAT TCAGATAAAG GACAAACCAT ATTTTGACTG 000800
000801 CTACTGACTT GTTGAACTGG CAGTCGGGGT CAACTTGGGA AGACAGCTGT GACCATAAAT ATTAAAGAAG ACAAAAGGAT 000880
000881 TCTTTGTGAC ACTGAGACCT TCTGCAGTAC CACAGTGGAG GAAATGCCAG TGTACACAAC TGGCCTCATT TAATTCCTGG 000960
000961 GAGGAGATAG TTTGGGATGC AGTGCTTGTT GTTGCTGAGC AGGCGATCAC AGCATGCACT GTGTTTCTTT CTTTGAGAAT 001040
001041 ATTTGAATCC TGCCTGAATA CTCGTAACAG ATGAGAGACG CAGGTTTTGA TAGCATAGAT TTACGCTGTC ATTAGTCATG 001120
001121 AGCTCTTGGG ACGAAAGTAA TTGGTTTTAT CCTGTTTAGA GTTAGACCCT GTGGTTGGGT ATGAAAGATG AGTGTCTGTA 001200
001201 AAAATCCTTC TTAGAAATGT ATTTCCTCAA GACTCTGTCT CAAAAAAAAA AAAAAGAAAT TTATTTCCTA GTTCTGTAAA 001280
001281 AATCGCTATA TTGAGTGTTC TCTATCACTT AATAATATAC TTATTATTAA GTGGACTTAA AGATATGCAG TGTATAAAAT 001360
001361 CAGCTAATTA CGTTAAACCA TGGTATCTCC CTTTATTGTG TTAGACTGAA TAGAACAAAC TTTAAAATAA TTTTTTAAAG 001440
001441 AATATATTTG AATTCATTTT GTTTGATAAT ATGTTTTTAT TCAGAAAAGC ATTTTATTAG CGCTAGGTGT GAACCCGAGC 001520
001521 CTTTTGCTAA ATACCAGCAG CAATCATGTC CTAGAGTTAA ATCCCAGAAA AATTGCCATA TTATATATTA AAGGTTCAAT 001600
001601 AAATTACAAT AAAGTATTTT TTCTTTAAAA AAAAAAAAAA AAAA

Labs working on this lncRNA

  • Department of Radiology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.

References

  1. 1.0 1.1 1.2 Wang S, Fan W, Wan B, Tu M, Jin F, Liu F, Xu H, Han P. Characterization of long noncoding RNA and messenger RNA signatures in melanoma tumorigenesis and metastasis. PLoS One. 2017 Feb 22;12(2).