LINC00659

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Revision as of 04:04, 5 November 2018 by Huma (talk | contribs) (Created page with " ==Annotation== ===Name=== LINC00659 ===Alias=== NA ===Disease=== Disease: colorectal cancer [http://www.ncbi.nlm.nih.gov/pubmed/29523145 (PMID:29523145)] Dysfunction type:...")
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Annotation

Name

LINC00659

Alias

NA

Disease

Disease: colorectal cancer (PMID:29523145)

Dysfunction type: expression

Description: Of the seletced lncRNAs, four lncRNAs named CCAT3, CCAT4, CCAT5, and CCAT6 (also named MYCLo-2) are upregulated in CRC cell lines, and two lncRNAs named CCAT7 and CCAT8 are downregulated in CRC cell lines. MYC-regulated lncRNAs, named MYCLos. The MYC-regulated MYCLos may function in cell proliferation and cell cycle by regulating MYC target genes such as CDKN1A (p21) and CDKN2B (p15), suggesting new regulatory mechanisms of MYC-repressed target genes through lncRNAs.


Function

Function Mechanism: NA (PMID:29523145)

Biological Process: pathogenic process

Description: NA