Difference between revisions of "LGALSL-DT"
(Created page with "''LGALSL-DT'', LGALSL divergent transcript aberrantly expressed in postmenopausal osteoporosis (PMOP). ==Annotated Information== ===Name=== ''LGALSL-DT'': LGALSL divergent tr...")
Latest revision as of 11:04, 26 December 2018
LGALSL-DT, LGALSL divergent transcript aberrantly expressed in postmenopausal osteoporosis (PMOP).
LGALSL-DT: LGALSL divergent transcript (HGNC:53951)
LGALSL-DT is a long non-protein coding RNA gene located at chromosome position 2p14. 
LOC105374771 may be involved in the pathogenesis of PMOP by regulating the expression of its nearby and co-expressed differentially expressed mRNAs and the pathway of osteoclast differentiation. LOC105374771 also regulates the expression of LGALSL. 
LOC105374771 was the most markedly downregulated lncRNA in PMOP. 
This lncRNA was co-expressed with 130 differentially expressed mRNAs (DEmRNAs), including ALPL, SOCS3, ADM, CD177 and SLPI. LOC105374771 may affect the pathogenesis of PMOP by regulating the expression of these DEmRNAs. 
Postmenopausal osteoporosis (PMOP) 
Labs working on this lncRNA
Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China
- Fei Q, Bai X, Lin J, Meng H, Yang Y & Guo A. Identification of aberrantly expressed long non-coding RNAs in postmenopausal osteoporosis[J]. International journal of molecular medicine. 2018, 41(6):3537-3550.
>ENST00000441630.1, Homo sapiens lncRNA LGALSL-DT cDNA antisense