Difference between revisions of "ENST00000425295.1"

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(Labs working on this lncRNA)
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==References==
 
==References==
[http://www.lncrnadb.org/kdm5bas1/ Annotation originally sourced from lncRNAdb.]
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<references>
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<ref name="ref1">Orom UA, Derrien T, Beringer M, Gumireddy K, Gardini A, Bussotti G, et al. Long noncoding RNAs with enhancer-like function in human cells[J]. Cell. 2010,143(1):46-58.</ref>(1)
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<ref name="ref2">Du Z, Fei T, Verhaak RG, Su Z, Zhang Y, Brown M, et al. Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer[J]. Nature structural & molecular biology. 2013,20(7):908-13.</ref>(2)
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</references>
  
 
{{basic|
 
{{basic|

Revision as of 09:21, 24 June 2016

Please input one-sentence summary here.

Annotated Information

Name

KDM5BAS1

Characteristics

Spliced two exon transcript. Multiple splice variants, ~550- ~750 nt in length, second exon varies. Expressed bidirectionally with KDM5B. In-vitro translation showed no sign of protein product.

Function

KDM5B-AS1 expression appears to stimulate KLHL12 gene expression (in HeLa cells). A gene located ~80kb from KDM5B-AS1 on the opposite strand.

Expression

Expressed in HeLa, K562 and GM12878 cells, plus a number of human tissues.

Conservation

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Misc

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Transcriptomic Nomeclature

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Regulation

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Allelic Information and Variation

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Evolution

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Labs working on this lncRNA

  • Centre for Genomic Regulation (CRG), UPF, Barcelona, Spain [1]


  • Center for Functional Cancer Epigeneitcs, Dana-Farber Cancer Institute, Boston, Massachusetts, USA [2]

References

  1. Orom UA, Derrien T, Beringer M, Gumireddy K, Gardini A, Bussotti G, et al. Long noncoding RNAs with enhancer-like function in human cells[J]. Cell. 2010,143(1):46-58.
  2. Du Z, Fei T, Verhaak RG, Su Z, Zhang Y, Brown M, et al. Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer[J]. Nature structural & molecular biology. 2013,20(7):908-13.

Basic Information

Transcript ID

ENST00000425295.1

Source

Gencode19

Same with

lnc-RP11-480I12.4.1-1:4

Classification

intergenic

Length

634 nt

Genomic location

chr1+:202780090..202781041

Exon number

2

Exons

202780090..202780498,202780817..202781041

Genome context

Sequence
000001 GACCTGGGCA ACCCCAGCCT GGAGGTGCCG GGGCCGGAGC TCCCAGAGGG CTGGGTGCGA GGCCTAGGCG GGGTCAGGTT 000080
000081 CGGGTTCCTA GGCCATAGCG GAGCTGCAGC CCAGGCGGCC GGAGCGGAAC CCAGCCCCGC TCCGAGTGCC ACGTCTCCAG 000160
000161 GAACCCCCTC CTTACTCTTG GACAACACTC CGCCCCCGCC CGGGCCTCCG TCCCCCAAAC CGCCCTCATT TGTGCAGCGC 000240
000241 CAGATCCTTC GGACACATCC CTAGGTGTCT CCATCCTCAT TCGGTCCATC CAACTCCCAG ACCTCACGTC AACCGGCTGC 000320
000321 ACCCCACTTT CCAGCCTGCG CCCCAGATCT GCAGCCTTCG CCCCTAGATA CACCCGCCTG GTGATGAGGC GCTCCTCGCG 000400
000401 TTCCTTCCGT CTCCAGTGCA CCGGCTTTCC CTCGTCCTCT GCGCAGTCCA TCTCAGCTCA TCTCTCCAAT TCAATGCCAT 000480
000481 CATCTCTCCT CACCATCTCT CGGTGCCCTG GAATGTTTGC TGTCAGATGT CCCCTGTGAA ACCCACAAAC GCTTGCGATT 000560
000561 TGGCCTCCTT GTTTTATTTT GTGTAGTCCT ACAACGTCTT GTTACTACCC CCTATTACAA CACTTATAAC TCAG
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