DEC1, a candidate tumor suppressor in 9q32
Approved symbol: DEC1
Approved name: deleted in esophageal cancer 1
HGNC ID: HGNC: 23658
Aliases: CTS9, Candidate Tumor Suppressor CTS9
RefSeq ID: NR_163556
DEC1 cDNA can suppress growth of some cancer cells in vitro, it is a candidate tumor suppressor in 9q32 .
The DEC1 gene is expressed in most normal human tissues, including the esophagus, but its expression is lower than normal, often absent, in more than half of the esophageal carcinomas examined .
>PREDICTED: Homo sapiens deleted in esophageal cancer 1 (DEC1), transcript variant X1
Labs working on this lncRNA
- Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
- Laboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Japan.
- Nishiwaki T, Daigo Y, Kawasoe T, Nakamura Y. Isolation and mutational analysis of a novel human cDNA, DEC1 (deleted in esophageal cancer 1), derived from the tumor suppressor locus in 9q32. Genes Chromosomes Cancer. 2000 Feb;27(2):169-76.
- Miura K, Suzuki K, Tokino T, Isomura M, Inazawa J, Matsuno S, Nakamura Y. Detailed deletion mapping in squamous cell carcinomas of the esophagus narrows a region containing a putative tumor suppressor gene to about 200 kilobases on distal chromosome 9q. Cancer Res. 1996 Apr 1;56(7):1629-34.