AA174084

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AA174084 long noncoding RNA potentially may play a role during Gastric Cancer development

Annotated Information

Name

AA174084 (also known simply as AA) is a gastric juice long noncoding RNA [1]

Alias

NA

Functions

lncRNA-AA174084 is a tumor-suppressor gene which was suggested to play a tumor-suppressor role in Gastric Cancer (GC) tumorigenesis (including tumor initiation, progression, metastasis and prognosis) and proposed as a potential biomarker for screening EGC. [2]

Function Mechanism: tumor suppression

Biological Process: pathogenic process

Description: biomarker

Regulation

AA174084 is down‐regulated in GC tissues compared with the paired, adjacent, normal tissues. [2]

Disease

Disease: gastric cancer [2]

Dysfunction type: expression

Description: AA174084 may have potential as marker for the early diagnosis of GC


Labs Working

Department of Biochemistry and Molecular Biology, and Zhejiang Provincial Key Laboratory of Pathophysiology,Ningbo University, China

References

<references> [1](1)

[2](2)
  1. 1.0 1.1 Virgilio E, Giarnieri E, Giovagnoli MR, Montagnini M, Proietti A, D’Urso R et al. Long non-coding RNAs in the gastric juice of gastric cancer patients[J]. Pathology - Research and Practice. 2018, 214(9):1239-1246.
  2. 2.0 2.1 2.2 2.3 Shao Y, Ye M, Jiang X, Sun W, Ding X, Liu Z et al. Gastric juice long noncoding RNA used as a tumor marker for screening gastric cancer[J]. Cancer. 2014, 120(21):3320-3328.