SPINT1-AS1:SPINT1 antisense RNA 1
RP11-532F12.5 might regulate the expression of neighboring protein-coding genes and influence the development and progression of melanoma . It is found that RP11-532F12.5 is co-expressed with its neighboring gene RHOV, which is an apoptosis-associated genes in the Rho GTPase family .
RP11-532F12.5 is downregulated with a log2 FC of -4.971 in metastatic melanoma (MM) when compared with normal skin tissues .
>NR_146466.1 Homo sapiens SPINT1 antisense RNA 1 (SPINT1-AS1), transcript variant 1, long non-coding RNA
Labs working on this lncRNA
- Department of Radiology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
- Wang S, Fan W, Wan B, Tu M, Jin F, Liu F, Xu H, Han P. Characterization of long noncoding RNA and messenger RNA signatures in melanoma tumorigenesis and metastasis. PLoS One. 2017 Feb 22;12(2).