SNHG18

From LncRNAWiki
Jump to: navigation, search

Annotated Information

Approved Symbol

SNHG18 (small nucleolar RNA host gene 18)

Small nucleolar RNA host gene 18 (SNHG18) promotes glioma cell radioresistance[1]

Chromosome

5p15.31

RefSeq(supplied by NCBI)

NR_045196

pubmed IDs

27788958

Characteristics

SNHG18 is located on chromosome 5 at 5p15.31 and has 3 exons encompassing 4410 nt.[1]

Expression

SNHG18 is upregulated in glioma and high SNHG18 expression is associated with the progression of primary glioma.[1]

Function

SNHG18 enhances the radioresistance of glioma cells.[1] SNHG18 promotes radioresistance of glioma cells by suppressing Sema5A expression.[1]

Labs working on this lncRNA

  • Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China; Department of Radiation Oncology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People's Republic of China.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Zheng, R., et al., Upregulation of Long Noncoding RNA Small Nucleolar RNA Host Gene 18 Promotes Radioresistance of Glioma by Repressing Semaphorin 5A. Int J Radiat Oncol Biol Phys, 2016. 96(4): p. 877-887.