PCED1B-AS1
PCED1B-AS1, a long noncoding RNA, is involved in the regulation of macrophage apoptosis and autophagy in active tuberculosis.
Contents
Annotated Information
Name
Approved symbol: PCED1B-AS1
Approved name: PCED1B-AS1: PCED1B antisense RNA 1
HGNC ID: HGNC:44166
RefSeq ID: NR_026544
Characteristics
Function
- PCED1B-AS1 modulates macrophage apoptosis and autophagy by targeting the miR-155 axis in active tuberculosis (TB)[1].
Regulation
Since PCED1B-AS1 modulates macrophage apoptosis and autophagy in a ceRNA manner, miR-155-targeted genes play vital roles in PCED1B-AS1-meditated macrophage apoptosis and autophagy [1].
Diseases
Tuberculosis[1].
Expression
PCED1B-AS1 is down-regulated in monocytes from patients with active TB[1].
Evolution
-
Sequence
>NR_026544.1 Homo sapiens PCED1B antisense RNA 1 (PCED1B-AS1), long non-coding RNA
000001 GGAAGCGGAA GACTAATGAC CGAAGCTTCA AGACTTTGAC ATGTGTGAAA ACATGAAATG ACCCTTGGCT CTTATTGTTC 000080
000081 TTGCTGGTGT GGTATGTTCA CGGCTGAAAA GATGGTCAGA AGGGGAAAGG AGGAAGTGAG AAGAAAGAAA CAGGGAAATG 000160
000161 ACAGAGTGTT GCTCAGTTAC CCAGGCTGGA GTGCAATGGC ATGATCTTGG CTCACTGCAG CCTCCACCTC CTGGGTTCAA 000240
000241 GCGGTTCTCG TGCCTCAGTC TCCCAAGTAG CTGGGATTAC AGGTATGCAC CACCATGCCC AGCCAATTTT GTATTTTTAG 000320
000321 TAGAGGCAGG GTTTCACCAT GTTGGCTAAG CTGGTCTTGA ACTCCTGACC TCAGGTGATC TACCTGCTTC AGCCTCTCAG 000400
000401 AGTGCTGGGA TTACAGGCAT GAGCCACCAA GCCCGGCCTG AAATACATTT AAATAAATGA AGATGGAGAA TCAGACATTA 000480
000481 CTTTCATTTA TCTGAATCTG GTGTAGTTTA ATTAATCTGT AATTGTAAGT CTTTGAATCA TATGTCAATA TTCTATTTTG 000560
000561 TTAGTCATGA TTTCTAAGTG TTACATAACT GTGGCCCCAG CCACTTTATA TTTTGGTATC ATGACAGAAG ACTCTGATTG 000640
000641 TGGTTATTTT CTACCTATGC ATTTATTCTT AGTGATATAT GTTGGTTAAA TTATGGCATA GTTTTAAAAT ACATGACAAA 000720
000721 AATAGCTAAC AGTAAAGAAA TGTCTTTGTT TCTGGTTGAA TAAACTGACC ACGCAAGGTT CCAATTTAAA ATAAATTCTA 000800
000801 AACGAATCAT GTTATTTTCC AAAACTGTTC CTCCTCTCAG TAAATGAAAT CAATATCCAC CCGGTTACCC CAAGACAGAA 000880
000881 ATCTCAAGAT CATCTGTGAC TCCTTCCTCT TCATCTGCCA CAAGAAGAGT AGCTTCTATC TCCAAAGCTA GTCTCTGATC 000960
000961 AGTCTACTTC TCTTCCTATA GCCTCTGCTT TAGTTCAAAT CTAGAATCCT GCTGTGGTGG TGCTGTGGCT TCCAAGTTCA 001040
001041 TCTTCTTCCA ATCCGTTCTC TAAACTACAG TCTTGCTCTT TCTAAGACTC AGATCTTATA ATTTTACTTC CCTTCATAGG 001120
001121 TTGAATTTAA CCTGCTAAAT CACATAAAAT TTTTCTGAAG ATACCAGCCT TTCTGCCTTA ATCAAACACA TTAGCCAAAT 001200
001201 CCATAGCATT ACTGGGATAA AGCCTGAAGA TCCCAAATTG ATAAGGCATC TGGATTCCCT TTGATAACAG TATTCAATAA 001280
001281 CAATGAACAC CTACTGAGTA TACTATTCCA AGCATTTAAA GTGTATCAAC TCTTTTCACA AAATCAACAA TAATTATTAT 001360
001361 TGCTACCATT TATTGAGAGT CTACTTTAAT CCAGGTGTTA CATATTCATG TATTCATTAT TATTACCTTT TTTTTTGAGA 001440
001441 CGAAATCTTG CTCTGTTGCC CAGGCTGGAG TGCGATGGCA TGATCTTGGC TCACGGCAAA CTCCGCCTCC CTGGTTCAAG 001520
001521 TGATTCTCCT GCCTCAGCCT CCCGAGTAGC CGGGATTACA GGCATGTGCC ACCATGCCCC GTTGGCCAGG CTGGTCTCGA 001600
001601 ACACCTTACC TCAGGTGATC CTCCCACCTT TGGGATTACA GGTGAGCCCA GCCTATTGTT ACCTTTAAAA CCACCCTGCA 001680
001681 GGGTAGCTCT TACTGTCTCC ATGAGGAATA TCAGAAAAGG GAAAGGACTT CCTGGAGGGC TGGTTCTGCC TCAAGCCAAT 001760
001761 CAGCTGACAC TAAGCAGTGA AGCCGGAATC TGAGGTCCCT CTGCCTGCCC TGGTCTTTGC TCACCCTGAC AACCAGACAC 001840
001841 CTCACTGTGT CCTGAGCAGC ATAGATGCCA CACGCACAGT GCCACATAGA GAAGGGTGAT GTAAATGAAA ATTAAAACAC 001920
001921 TGTGACAAAG TCAAGCAGGG CATTTGTTTT TGTTGTTGTT AAGTTATTTT TGGTAGATAC AGGGTCTCAC TATGTTGACC 002000
002001 AGGCTGGTCT TGAACTCCTG GGCTCAAGCA ATCTGCCTGC CTCAGCCTCT CAGAATGTTG GGATTATAGA CATGAACCAC 002080
002081 TGCACCCGGC CAGTGTCAGT CTTTGTTCCC TACAAGTGAA ATCAAAACAG CCTCACGCCT GTAAACCCAG CAGTTTAGGA 002160
002161 GCCCAAGGTG GAAGGATCGC TTGAGCCCAG GAGTTTGAAA CCAGTCTAGG CAACATAGTG AGACCCTATC TATACAAAAA 002240
002241 TAAAAATAGC CTGGGCAGGG TGACTCATGC CTATAATCCC AGTACTTTGG GAGGCCAAGG TGGGTGCATC ACTTGAGGTC 002320
002321 AGGAGTTCGA GACCAGCCTG GCTAACATGG AGAAACCCTG TCTCTATTAA AAATACGCCT GTAGTCCCAG TTACTCGGGA 002400
002401 CGCTGAGGCA GGACTGCTTG AACCTGGGAG GTAGAGGTTG CAGTGAGCCG AGATCGCGAT ACTGCACTCT AGAGCCTGAG 002480
002481 TGACAGAGTG AGACTCCGTC TC
000081 TTGCTGGTGT GGTATGTTCA CGGCTGAAAA GATGGTCAGA AGGGGAAAGG AGGAAGTGAG AAGAAAGAAA CAGGGAAATG 000160
000161 ACAGAGTGTT GCTCAGTTAC CCAGGCTGGA GTGCAATGGC ATGATCTTGG CTCACTGCAG CCTCCACCTC CTGGGTTCAA 000240
000241 GCGGTTCTCG TGCCTCAGTC TCCCAAGTAG CTGGGATTAC AGGTATGCAC CACCATGCCC AGCCAATTTT GTATTTTTAG 000320
000321 TAGAGGCAGG GTTTCACCAT GTTGGCTAAG CTGGTCTTGA ACTCCTGACC TCAGGTGATC TACCTGCTTC AGCCTCTCAG 000400
000401 AGTGCTGGGA TTACAGGCAT GAGCCACCAA GCCCGGCCTG AAATACATTT AAATAAATGA AGATGGAGAA TCAGACATTA 000480
000481 CTTTCATTTA TCTGAATCTG GTGTAGTTTA ATTAATCTGT AATTGTAAGT CTTTGAATCA TATGTCAATA TTCTATTTTG 000560
000561 TTAGTCATGA TTTCTAAGTG TTACATAACT GTGGCCCCAG CCACTTTATA TTTTGGTATC ATGACAGAAG ACTCTGATTG 000640
000641 TGGTTATTTT CTACCTATGC ATTTATTCTT AGTGATATAT GTTGGTTAAA TTATGGCATA GTTTTAAAAT ACATGACAAA 000720
000721 AATAGCTAAC AGTAAAGAAA TGTCTTTGTT TCTGGTTGAA TAAACTGACC ACGCAAGGTT CCAATTTAAA ATAAATTCTA 000800
000801 AACGAATCAT GTTATTTTCC AAAACTGTTC CTCCTCTCAG TAAATGAAAT CAATATCCAC CCGGTTACCC CAAGACAGAA 000880
000881 ATCTCAAGAT CATCTGTGAC TCCTTCCTCT TCATCTGCCA CAAGAAGAGT AGCTTCTATC TCCAAAGCTA GTCTCTGATC 000960
000961 AGTCTACTTC TCTTCCTATA GCCTCTGCTT TAGTTCAAAT CTAGAATCCT GCTGTGGTGG TGCTGTGGCT TCCAAGTTCA 001040
001041 TCTTCTTCCA ATCCGTTCTC TAAACTACAG TCTTGCTCTT TCTAAGACTC AGATCTTATA ATTTTACTTC CCTTCATAGG 001120
001121 TTGAATTTAA CCTGCTAAAT CACATAAAAT TTTTCTGAAG ATACCAGCCT TTCTGCCTTA ATCAAACACA TTAGCCAAAT 001200
001201 CCATAGCATT ACTGGGATAA AGCCTGAAGA TCCCAAATTG ATAAGGCATC TGGATTCCCT TTGATAACAG TATTCAATAA 001280
001281 CAATGAACAC CTACTGAGTA TACTATTCCA AGCATTTAAA GTGTATCAAC TCTTTTCACA AAATCAACAA TAATTATTAT 001360
001361 TGCTACCATT TATTGAGAGT CTACTTTAAT CCAGGTGTTA CATATTCATG TATTCATTAT TATTACCTTT TTTTTTGAGA 001440
001441 CGAAATCTTG CTCTGTTGCC CAGGCTGGAG TGCGATGGCA TGATCTTGGC TCACGGCAAA CTCCGCCTCC CTGGTTCAAG 001520
001521 TGATTCTCCT GCCTCAGCCT CCCGAGTAGC CGGGATTACA GGCATGTGCC ACCATGCCCC GTTGGCCAGG CTGGTCTCGA 001600
001601 ACACCTTACC TCAGGTGATC CTCCCACCTT TGGGATTACA GGTGAGCCCA GCCTATTGTT ACCTTTAAAA CCACCCTGCA 001680
001681 GGGTAGCTCT TACTGTCTCC ATGAGGAATA TCAGAAAAGG GAAAGGACTT CCTGGAGGGC TGGTTCTGCC TCAAGCCAAT 001760
001761 CAGCTGACAC TAAGCAGTGA AGCCGGAATC TGAGGTCCCT CTGCCTGCCC TGGTCTTTGC TCACCCTGAC AACCAGACAC 001840
001841 CTCACTGTGT CCTGAGCAGC ATAGATGCCA CACGCACAGT GCCACATAGA GAAGGGTGAT GTAAATGAAA ATTAAAACAC 001920
001921 TGTGACAAAG TCAAGCAGGG CATTTGTTTT TGTTGTTGTT AAGTTATTTT TGGTAGATAC AGGGTCTCAC TATGTTGACC 002000
002001 AGGCTGGTCT TGAACTCCTG GGCTCAAGCA ATCTGCCTGC CTCAGCCTCT CAGAATGTTG GGATTATAGA CATGAACCAC 002080
002081 TGCACCCGGC CAGTGTCAGT CTTTGTTCCC TACAAGTGAA ATCAAAACAG CCTCACGCCT GTAAACCCAG CAGTTTAGGA 002160
002161 GCCCAAGGTG GAAGGATCGC TTGAGCCCAG GAGTTTGAAA CCAGTCTAGG CAACATAGTG AGACCCTATC TATACAAAAA 002240
002241 TAAAAATAGC CTGGGCAGGG TGACTCATGC CTATAATCCC AGTACTTTGG GAGGCCAAGG TGGGTGCATC ACTTGAGGTC 002320
002321 AGGAGTTCGA GACCAGCCTG GCTAACATGG AGAAACCCTG TCTCTATTAA AAATACGCCT GTAGTCCCAG TTACTCGGGA 002400
002401 CGCTGAGGCA GGACTGCTTG AACCTGGGAG GTAGAGGTTG CAGTGAGCCG AGATCGCGAT ACTGCACTCT AGAGCCTGAG 002480
002481 TGACAGAGTG AGACTCCGTC TC
Labs working on this lncRNA
- Fourth Tuberculosis Internal Medicine Department, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, 453100, PR China
