NONHSAT040920

From LncRNAWiki
Jump to: navigation, search
Please cite: Chunlei Yu (2016) lncRNA: "NONHSAT040920" in LncRNAWiki, available at http://lncrna.big.ac.cn/index.php?title=NONHSAT040920&oldid=1272352 (Last update: Jul 01, 2016). [See details]

PWRN1, Prader-Willi region non-protein coding RNA 1 of 1451 bp, which was located between NDN and C15orf2, may play a role in PWS (Prader–Willi/Angelman syndrome) with C15orf2.

Contents

Annotated Information

Name

PWRN1:Prader-Willi region non-protein coding RNA 1(HGNC nomenclature)

NCRNA00198, "non-protein coding RNA 198"[1]

Characteristics

phisical maps[1]

PWRN1,a 1451 bp Prader-Willi region non-protein coding RNA 1,located between NDN and C15orf2 in 15q11.2[1].

Function

PWRN1 may functions with C15orf2 in PWS (Prader–Willi/Angelman syndrome)[1].

Disease

Prader-Willi syndrome

Expression

Tissue-specific expression analysis of PWRN1 detected by reamplification of RT-PCR products for exons 23-26[1]

The expression of PWRN1 is most abundant in testis, but also present at low levels in several other tissues, including fetal brain[1].

RT-PCR primer pairs used for PWRN1 were as follows,

Primer Sequences
PWRN2-AK058147-F2 5'-AACACGGAGATGCATTGACA-3'[1]
Ex26R 5'-ACCTGGGCAACAATTGACTC-3'[1]
PWRN1-Exon19-F 5'-GCAACATTCGAAACCCAGGTGCT-3'[1]
Ex26R 5'-ACCTGGGCAACAATTGACTC-3'[1]
AK058147-F2 5'-AACACGGAGATGCATTGACA-3'[1]
AL704599-R2 5'-TCTGTTTCCCAAGCTGGAGT-3'[1]
PWRN1-Exon2-F 5'-GATTCCCCAGCTGATCCTCG-3'[1]
PWRN1-Exon8-R 5'-AGAAGGGTGTCAATGCATCACCG-3'[1]
Ex23F 5'-GCCTCCTTTATTGAGAAATGTTTT-3'[1]
Ex26R 5'-ACCTGGGCAACAATTGACTC-3'[1]

Allelic Information and Variation

PWRN1 is biallelically expressed in testis and kidney, but monoallelically in fetal brain[1].

Labs working on this lncRNA

  • Institut für Humangenetik, Universitätsklinikum Essen, Hufelandstrasse 55, 45122 Essen, Germany.[1]

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 Buiting K, Nazlican H, Galetzka D, Wawrzik M, Gross S, Horsthemke B. C15orf2 and a novel noncoding transcript from the Prader-Willi/Angelman syndrome region show monoallelic expression in fetal brain[J]. Genomics. 2007,89(5):588-95.

Basic Information

Transcript ID

NONHSAT040920

Source

NONCODE4.0

Same with

PWRN1, NCRNA00198

Classification

intergenic

Length

1451 nt

Genomic location

chr15+:24803299..24832926

Exon number

9

Exons

24803299..24803468,24811803..24811947,24813044..24813329,24814930..24814956,24815179..24815275,24819657..24819960,24820054..24820150,24825374..24825477,24832714..24832926

Genome context

Sequence
000001 AGAACAGGCA GAGGCAGTTC AGGGGTATTC TGGTTGCCTT ACCCAGCTCT GAAGTCTGTC AGCCTCTTCA GATGTCACTT 000080
000081 GCCATGTGGT AAGGAAGTGT AGTCAGCAGC TGGTGCAGTG GGAAGAAGAG AAAGGAAGTT CCCCAAGACA AAAACATCTC 000160
000161 GGCAGACCGT GATCATGGGC TACATTCTCC GTACCAGCTT CATAGCTCCA GTGAGAAAAT AAATTCCTGC ATCCAGGAGA 000240
000241 TGTGGAGTAA GAGATACAGC TGCCCTTGAC CATATTTCTT ACTTCCGAGA AGATCGTAGC AGTAATTCAG TCTTCAGGGA 000320
000321 ACACCAAGGC CTGTTTGATT TTCCAAGTAT CAACAAGTGG AGTTGACAAG AGTGACAAGT GGTCAGAGCA AAGCATTTCA 000400
000401 TGATGACTGT AACGTGCCTG TGTCAGCAGC GACTGCTTAC AGTGAGATTC ACATGACCAT CGTTTATGAC ATAGGAAGAA 000480
000481 TAAAAGGAGA GAGAGAGAGA AAGATAGGTA GTTGATCAAA ATGAAGAATT GGATTTGGAA AGCAACTTCG AATAGTCTCT 000560
000561 GCTTATATTT CTGAGATTAA GGCAAACAGT CTCAAGAATC TCATCCAGGA TACCTCATCA CAGGCTGGAG TGCAGTGTCA 000640
000641 TGAGCTTGGC TCACTACAGC CTCCATCTTC TGTGCTTAAG GATCCTTCCC TCTCAACCTC CAAGGTAGCT GAGACTACAG 000720
000721 GCAACATTCG AAACCCAGGT GCCACTCCTT CAGGAAGGTA CCATCAAGCT CCAAGGACTC ATCCTCTTTC TCCTTCCCCA 000800
000801 CTACCTAGTC ATTAGAGCGT CAGCATCCAC TTCCTGAAAG GAAGATGCCT GTTTTTCACA TATCCCAGAA AGCCTCATTT 000880
000881 TAGGACAGCA TTTAGCAGAG TGTATTCAGG ATCCCACTAA CCTTTTCGGA AGACATGACT TCCAGATGAT ATAAGGCAAG 000960
000961 AATAAGAAAT TTCAGTGACA GGGAACAGAA ATCATATTTC TGCATTCAGG ATCATGTTTT CTTGGCTCCA TCAGGAACTG 001040
001041 TGCAGGACTG TGCACTCTGT TGATACTCAC ATGGTGGAAT TATATTGCCC TTGGCCAACC CTAAAGCCAT CAAGATAGCA 001120
001121 GCAACTACTC TATCATTACT GTACCACCAC CTGTATGGAT CTCGTTGCCC ATATGAAACT GAGTAAGGAA CAATGTGCAT 001200
001201 CACACTCACA GAGAAAGATG GACAAGTTTG GAATAATTCA CTGTCGAAGT CTTCTTGAGC TGAGCAGTCA TGTGAGCTTG 001280
001281 GAAGATGATC CCTCTCCAGC TGATCCTTCA GCTCAGGCCA TCATCTACAT CTGGATTCCT GACCCGGAGA AACTATGAGT 001360
001361 AATGTGTGCT GCTTTTGAGC CACTAAGCTA CATGGTAATA GGCTATGCTT CAATAAACAA TAATACACTT GATGATAAAA 001440
001441 AAAAAAAAAA A
[back to top]
Please cite: Chunlei Yu (2016) lncRNA: "NONHSAT040920" in LncRNAWiki, available at http://lncrna.big.ac.cn/index.php?title=NONHSAT040920&oldid=1272352 (Last update: Jul 01, 2016).
ContributorContribution Score*Edit Count#Summed Edit QuantityΛAveraged Edit QualityLatest Edit TimeEdit Details
Chunlei Yu2.168121700.9992016-06-25 14:36:04[show]
Contributors with score < 1 are excluded from the authorship.
ContributorContribution Score*Edit Count#Summed Edit QuantityΛAveraged Edit QualityLatest Edit TimeEdit Details
Lin Liu0.03613612016-07-01 22:00:46[show]
Note: For each edit version that is contributed by a specific person, his/her contribution is quantified as its edit quality multiplied by its edit quantity; the edit quantity amounts to the edit distance in comparsion with its previous version (that is, the minimum number of edit operations required to transform one string into the other), and the edit quality corresponds to whether the edit persists in comparison with the last version, ranging from -1, when the edit is entirely reverted (short-lived), to 1, indicating that the edit is totally preserved in the last version (long-lived). Please also note that contribution quantification may take time to reflect recent edits.
*Since one person may perform many discontinuous edits for a wiki page, contribution score is the sum of quantified contributions over all participated edits.
#Multiple successive edits provided by a researcher are counted as one edit.
ΛSummed edit quantity is the sum of edit quantities over all participated edits.
Averaged edit quality is the edit quality normalized over all participated edits.
Personal tools
Namespaces

Variants
Actions
Navigation
About
ScienceWikis
Toolbox