Disease: loeys-dietz syndrome (PMID:26617788)
Dysfunction type: interaction
Description: LncRNA AK056155 was differentially expressed in peripheral blood circulating endothelial cells between normal patients and LDS patients by bioinformatics. AK056155 was also overexpressed in aortic aneurysm patients by RT-PCR.These results indicate that AK056155 involved in the development of Loeys-Dietz syndrome through AKT/PI3K signaling pathway.
Function Mechanism: NA (PMID:26617788)
Biological Process: pathogenic process
Description: therapy target