MELTF-AS1 (MELTF antisense RNA 1)
RefSeq(supplied by NCBI)
Compared with corresponding adjacent, histological normal tissues, MELTF-AS1 was significantly upregulated in human osteosarcoma tissues (P<0.0001). FOXP4 protein is upregulated in osteosarcoma tissues and positively correlated with MELTF-AS1 expression.
Knockdown of MELTF-AS1 inhibits osteosarcoma cell migration, invasion and proliferation. However,knockdown of MELTF-AS1 promotes osteosarcoma cell apoptosis in vitro.
Labs working on this lncRNA
- Department of Orthopaedic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, P.R. China.
- Department of Anatomy, Guangzhou Medical University, Guangzhou, Guangdong 510182, P.R. China.
- Yin, Z., et al., Overexpression of long non-coding RNA MFI2 promotes cell proliferation and suppresses apoptosis in human osteosarcoma. Oncol Rep, 2016. 36(4): p. 2033-40.