MDS2 (myelodysplastic syndrome 2 translocation associated)
RefSeq(supplied by NCBI)
The MDS2 gene is approximately 13 kb and is ﬂanked by E2F2 and ID3 at its 5' end (telomeric) and by RPL11 and TCEB3 at its 3' end (centromeric) and gives rise to four alternatively spliced products. The predicted ETV6-MDS2 fusion product contains 58 amino acids, starting at the ﬁrst ATG of ETV6 and ending in aTGA stop codon only four amino acids after ETV6 exon 2.
Oligonucleotide primers' sequences of MDS2 are showed as follow.
Labs working on this lncRNA
- Department of Genetics, University of Navarra, Pamplona, Spain.
- Odero, M.D., et al., A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome. Genes Chromosomes Cancer, 2002. 35(1): p. 11-9.