LINC02590

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LINC02590, long intergenic non-protein coding RNA 2590 involved in the carcinogenesis of gastric cancer.

Annotated Information

Name

LINC02590: long intergenic non-protein coding RNA 2590 (HGNC:53861)

Alias

AC016735.2 (HGNC:53861)

Characteristics

LINC02590 is a long non-protein coding RNA gene located at chromosome position 2p21. [1]

Function

AC016735.2 may regulate ALOX15 and have a role in the progression of GC.[1]

Regulation

According to the findings of the transcriptome sequencing and bioinformatics analyses, AC016735.2 was upregulated and RT-qPCR validation confirmed that AC016735.2 was upregulatedin GC tissues compared with normal adjacent tissues.[1]

Expression

Experiment Forward primer Reverse primer
RT-qPCR 5'-CTGCTTCTCACTGCCTCG- 3' 5'-TTTCCCAAATGGTCCTCC- 3'[1]

It is a differentially expressed lncRNA in gastric cancer tissue.[1]

Disease

Gastric cancer [1]

Labs working on this lncRNA

Department of Laboratory Medicine, Shanghai Shuguang Hospital Affiliated with Shanghai University of TCM, Shanghai 200021, P.R. China

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Wang Y & Zhang J. Identification of differential expression lncRNAs in gastric cancer using transcriptome sequencing and bioinformatics analyses[J]. Molecular medicine reports. 2018, 17(6):8189-8195.

Sequence

>ENST00000438158.1, Homo sapiens lincRNA LINC02590cdna

000001 ACCTCTTTCT CTGCTTTCAT TTCGTCGGAC TGGCTGCGCC CCTACCTTTC TCTCTGAATC CATCACACCC CTCCCTGACT 000080
000081 CCTGCCAGGC CATGGCAGAA TTGCTGTTCC CAGGAAGGCA GGCCTGGCCT GGGCTGAAAA GCAGATCTGG GTTCTAATCT 000160
000161 CCCTTCTGCA TGGACCTGCG GGTGACACAA GCTTGGTGCC TTCTCCTCTC TGAACTTCAA GTCCTTACTT GGACAAGATG 000240
000241 GCCTGGCTCC TCCCAGCCCT GGATTTGGGG ATGCTCCGAT GCTGCCTGGG AGCCCAGTCT GATCATGGTG GCCTGGAAAT 000320
000321 CAAGGCTAAG CGAAAGGAAA GCCTGAAAGA GCTGCACTCT AAGCACCACA GCAGGACTTG CCCCTGAATG GAGATGGGGC 000400
000401 TGGGGCAGGA AGGTGGCAGG GAGGGGCTGG GCCCTGTGAC TGTCACCTCC AGGTTGGAGG AGTGGGGAGG GAAAGGCAGG 000480
000481 GCAGGGTGCG TTATCACACA CACACTCACC CACATACACT CAAGCACACA CCACAGAGTC CAAGGAAAAC CTGTTTCTGT 000560
000561 CCTAGCACT