LINC02231:long intergenic non-protein coding RNA 2231
Long noncoding RNA RP11-766N7.4 is located on the reversed strand in 12q14.3 region with a length of 447 bps .
RP11-766N7.4 expression is negatively correlated with lymph node metastasis and tumor stage, and RP11-766N7.4 inhibites cellular migration and invasion by suppressing EMT (Epithelial-Mesenchymal Transition) process .
RP11-766N7.4 is remarkably down-regulated in Esophageal squamous cell carcinoma(ESCC) tissue samples compared with the paired adjacent tissues .
Esophageal squamous cell carcinoma 
Labs working on this lncRNA
- Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China.
- Yao GL, Pan CF, Xu H, Wei K, Liu B, Zhai R, Chen YJ. Long noncoding RNA RP11-766N7.4 functions as a tumor suppressor by regulating epithelial-mesenchymal transition in esophageal squamous cell carcinoma. Biomed Pharmacother. 2017 Apr;88:778-785.