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Annotated Information


LINC02231:long intergenic non-protein coding RNA 2231

RP11-766N7.4 [1]


Long noncoding RNA RP11-766N7.4 is located on the reversed strand in 12q14.3 region with a length of 447 bps [1].


RP11-766N7.4 expression is negatively correlated with lymph node metastasis and tumor stage, and RP11-766N7.4 inhibites cellular migration and invasion by suppressing EMT (Epithelial-Mesenchymal Transition) process [1].


RP11-766N7.4 is remarkably down-regulated in Esophageal squamous cell carcinoma(ESCC) tissue samples compared with the paired adjacent tissues [1].


Esophageal squamous cell carcinoma [1]

Labs working on this lncRNA

  • Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China.


  1. 1.0 1.1 1.2 1.3 1.4 Yao GL, Pan CF, Xu H, Wei K, Liu B, Zhai R, Chen YJ. Long noncoding RNA RP11-766N7.4 functions as a tumor suppressor by regulating epithelial-mesenchymal transition in esophageal squamous cell carcinoma. Biomed Pharmacother. 2017 Apr;88:778-785.