LINC01930

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Annotated Information

Name

LINC01930:long intergenic non-protein coding RNA 1930

EU358092 [1]

Characteristics

EU358092 is a brain-expressed RNA, within the schizophrenia-associated region at 1p21.3 (chr1:98,399,030–98,407,302; GRCh37/hg19) [1]. It is 869 bp in length and has two exons [1].

Function

EU358092 shows a potentially important role in the aetiology of schizophrenia, and its expression is modulated in response to psychoactive drug treatment in the human SH-SY5Y neuroblastoma cell line [1].

Expression

Comparison of MIR137 and EU358092 expression in vivo [1].

EU358092 shows a similar expression pattern to that of MIR137, with highest expression restricted to the brain and pituitary gland [1].

Disease

Schizophrenia [1]

Labs working on this lncRNA

  • Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, The University of Liverpool, Liverpool L69 3BX, UK.

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Gianfrancesco O, Warburton A, Collier DA, Bubb VJ, Quinn JP. Novel brain expressed RNA identified at the MIR137 schizophrenia-associated locus. Schizophr Res. 2017 Jun;184:109-115.