LINC01857：long intergenic non-protein coding RNA 1857
The long non-coding RNA transcript AC079767.4 (Ensembl ID ENST00000429730) is encoded by gene AC079767.4 (Ensembl ID ENSG00000224137).
AC079767.4 is a highly susceptible lncRNA in tuberculosis. Haplotype [ACAC], representing four AC079767.4 variants in Western Chinese Han population, is found to slightly decrease TB risk (p = 0.045) .
AC079767.4 transcript is down-regulated in both the active TB group and latent tuberculosis infection (LTBI) group compared with healthy controls, and its expression level is elevated in the LTBI group when compared to the active TB group .
>NR_135567.1 Homo sapiens long intergenic non-protein coding RNA 1857 (LINC01857), transcript variant 2, long non-coding RNA
Labs working on this lncRNA
- Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, 610041, P.R. China.
- Zhao Z, Zhang M, Ying J, Hu X, Zhang J, Zhou Y, Zhou Y, Song X, Ying B.Significance of genetic polymorphisms in long non-coding RNA AC079767.4 in tuberculosis susceptibility and clinical phenotype in Western Chinese Han population. Sci Rep. 2017 Apr 19;7(1):965.