LINC01852

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Annotated Information

Effect of LINC01852 on cell growth in vivo[1]
Effect of LINC01852 on cell invasion[1]

Approved Symbol

LINC01852 (long intergenic non-protein coding RNA 1852)

Synonyms

ENST00000434223

Chromosome

15q14

RefSeq(supplied by NCBI)

XR_001751481

pubmed IDs

26883250

Characteristics

LINC01852 is localized in Human chromosome 15 (38363831–38364884) and has a transcript of about 964 bp.[1]

Expression

The expression level of LINC01852 is significantly downregulated in cancerous tissues compared with paired adjacent normal tissues.[1] LINC01852 overexpression induced a significant increase in the percentage of cells in G0/G1 phase as determined by flow cytometric assay .[1]

The primer sequences used in this study were as follows:

Experiment Forward primer Reverse primer
qRT-PCR 5'-GCAAGTGTTGAAGGACGACGAT-3′ 5′CAAGGAGGCATACACGGAGTT-3′[1]

Function

Overexpression of LINC01852 inhibits proliferation and migration of NSCLC cells in vitro.[1]

Labs working on this lncRNA

  • School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
  • Department of Pathology, the Affiliated Cancer Hospital to Zhengzhou University, Zhengzhou, China.

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Chai, X., X. Ye, and Y. Song, Long noncoding RNA ENST00000434223 suppressed tumor progression in non-small cell lung cancer. Tumour Biol, 2016. 37(8): p. 10851-60.