LAMC1-AS1

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Annotation

Name

Approved symbol: LAMC1-AS1

Approved name: LAMC1 antisense RNA 1

Alias symbols: lnc-LAMC2-1:1

HGNC ID: HGNC:52645

Ensembl ID: ENSG00000224468

LncBook transcript ID: HSALNT0018525

Characteristics

-

Function

  • Rs2147578 in lnc-LAMC2-1:1 might be a genetic modifier for the development of colorectal cancer(CRC)[1].
  • The lnc-LAMC2-1:1 rs2147578 polymorphism may be a risk factor for developing childhood acute lymphoblastic leukemia (ALL)[2].

Regulation

-

Diseases

Colorectal cancer (CRC)[1]

Acute lymphoblastic leukemia (ALL)[2]

Expression

-

Evolution

-

Sequence

>NR_149048.1 Homo sapiens LAMC1 antisense RNA 1 (LAMC1-AS1), long non-coding RNA

000001 GTGGCACGAT AACAGCTCAC TATCACCTCA AACTCAAGTG ATGCACCTGC TTCAGTCTCC CGGGTAGCTA GGACTACAGG 000080
000081 CGTGTAGCAC CACACCCAGC TAATTTTTAA AATAATTTGA AGAGACGAGA TACTGCCAGC AAGATGAGTT AAGAAAAATC 000160
000161 ACTGTTTAGT TGTACAATGA TACTGGACCA TAAATGCTAC CCTAGCTGGC AATATATCTT CAAAATATAA AAAGAAACTC 000240
000241 CTCAGACCAC AGTGTTCTAC TTAGGGCAAG GTCCACAGAA GGCACCTAAT GAAAATGACC CACACTGAGG GACTATGTTT 000320
000321 TCTGGCAGCA GTGAACGACG GCCTCTTCTT TGCCACTGAA AGTGAGCAAG TAACCACAAG TTCGTGTATG TCATTACCGT 000400
000401 GATTGCTACA CCCAACTGGA AAAAGAATAT TCCTACTGTG ACTCCATTAA AGTCTTTTCA AAGCAAA

Labs working on this lncRNA

  • Research Center for Medicine and Biology, Zunyi Medical University, Zunyi, Guizhou, China.

References

  1. 1.0 1.1 Gong J, Tian J, Lou J, et al. A functional polymorphism in lnc-LAMC2-1: 1 confers risk of colorectal cancer by affecting miRNA binding[J]. Carcinogenesis, 2016, 37(5): 443-451.
  2. 2.0 2.1 Hashemi M, Bahari G, Naderi M, et al. Association of lnc-LAMC2-1: 1 rs2147578 and CASC8 rs10505477 polymorphisms with risk of childhood acute lymphoblastic leukemia[J]. Asian Pacific journal of cancer prevention: APJCP, 2016, 17(11): 4985.