Approved Symbol: FOXC2-AS1
Approved Name: FOXC2 antisense RNA 1
RefSeq ID: NR_125795
Ensembl ID: ENSG00000260944
LncBook transcript ID: HSALNT0288979
- Loss of function revealed that silenced FOXC2-AS1 significantly suppressed the proliferation ability, and flow cytometric analysis illustrated the influence of FOXC2-AS1 on cell cycle and apoptosis rate. Cyclin D1, cyclin D2, and cyclin D3 were all partly positively modulated by FOXC2-AS1 in breast cancer (BC)..
FOXC2-AS1 was significantly increased in BC tissues and cell lines, and Kaplan–Meier survival analysis indicated that a high level of FOXC2-AS1 was associated with poor prognosis of BC patients.
|Experiment||Forward primer||Reverse primer|
|Quantitative real-time PCR||5'-TTCATCGGCTGCGTATTCG- 3'||5'-TTGCCTTCTAGTCGCCTCC- 3'|
>gi|672890592|ref|NR_125795.1| Homo sapiens FOXC2 antisense RNA 1 (FOXC2-AS1), long non-coding RNA
Labs working on this lncRNA
- Department of Breast Surgery, the Affiliated Hospital of Guizhou Medical University, Guizhou, P.R. China
- Yang H, Chen T, Xu S, Zhang S, Zhang M. Long Noncoding RNA FOXC2-AS1 Predicts Poor Survival in Breast Cancer Patients and Promotes Cell Proliferation. Oncol Res. 2019 Feb 5;27(2):219-226.