Disease: colorectal cancer (PMID:25921151)
Dysfunction type: expression
Description: To validate the microarray results, we randomly selected 6 differentially expressed lncRNAs (TCONSNA00026506, ENST00000468960, NRNA038990, ENST00000575202, ENST00000539009 and ENST00000544591) between CRR-HCT116 and parental HCT116 cells to confirm their expression levels by qPCR. Changes in lncRNA expression are involved in 5-FU-based CRR in CRC cells.
Function Mechanism: NA (PMID:25921151)
Biological Process: pathogenic process