DINOL (damage induced long noncoding RNA)
RefSeq(supplied by NCBI)
DINO encodes a p53-dependent DNA damage-induced transcript. DINO stabilizes p53 and enhances regulation of its target genes. Loss of DINO abrogates DNA damage-induced gene regulation and cell cycle arrest.
Labs working on this lncRNA
- Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, California, USA.
- Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA.
- Schmitt, A.M., et al., An inducible long noncoding RNA amplifies DNA damage signaling. Nat Genet, 2016. 48(11): p. 1370-1376.