DARS-AS1:DARS antisense RNA 1
DARS-AS1 (chr2: 136742746-136765112) is anti-sense to DARS (aspartyl-tRNA synthetase) .
DARS-AS1, regulated by HIF-1, is found to inhibit apoptotic cell death in the renal tubular epithelial cells under hypoxia .
HIF-1 binds to the Hypoxia-Responsive Elements (HREs) in the promoter region of DARS-AS1 and up-regulates its expression under hypoxia .
Renal disease 
DARS-AS1 is commonly up-regulated under hypoxia in tubular cells .
>NR_110199.1 Homo sapiens DARS antisense RNA 1 (DARS-AS1), transcript variant 1, long non-coding RNA
Labs working on this lncRNA
- Division of Nephrology and Endocrinology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
- Mimura I, Hirakawa Y, Kanki Y, Kushida N, Nakaki R, Suzuki Y, Tanaka T, Aburatani H, Nangaku M. Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia. Physiol Rep. 2017 Apr;5(8). pii: e13203.