DANT1 (DXZ4 associated non-coding transcript 1, proximal)
DANT1 generates an array-traversing transcript (ATT) with the longest DANT1 transcript entirely contained within, but anti-sense to, the longest predicted DANT2 transcript. DANT1 produces both non-ATT and ATT transcript isoforms. Low levels of H3K9me3 can be observed at the DANT1 promoter in hESC.
DANT1 lncRNA is linked to changes in DXZ4 chromatin.
The short DANT1 transcript detected in hESCs was of particularly low abundance, and could only be confidently detected in prostate, testis, trachea and spinal cord.
Labs working on this lncRNA
- Department of Biological Science, Florida State University, 319 Stadium Drive, King 3076, Tallahassee, FL, 32306-4295, USA.
- NHLBI, National Institutes of Health, 10 center Drive, Building 10 Rm 6D12, Bethesda, MD, 20892, USA.
- Department of Biological Science, Florida State University, 319 Stadium Drive, King 3076, Tallahassee, FL, 32306-4295, USA. 
- 1: Figueroa DM, Darrow EM, Chadwick BP. Two novel DXZ4-associated long noncoding RNAs show developmental changes in expression coincident with heterochromatin formation at the human (Homo sapiens) macrosatellite repeat. Chromosome Res. 2015 Dec;23(4):733-52. doi: 10.1007/s10577-015-9479-3.