CLMAT3

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Annotated Information

Approved Symbol

CLMAT3

Approved Name

colorectal liver metastasis associated transcript 3

The CLMAT3 expression levels in 90 paired CRC and normal tissue samples were analyzed via a qRT-PCR assay[1]

Synonyms

SPARC-AS1

RefSeq(supplied by NCBI)

NR_109873

Characteristics

CLMAT3 is located on human chromosome 14 (chr14:101379770-101381326, hg19) [1].

Expression

CLMAT3 is significantly up-regulated in the cancerous tissues comparing with the normal colorectal tissues, and high CLMAT3 expression strongly correlates with liver metastasis and lymph node metastasis, and shorter median overall survival duration [1].

Function

CLMAT3 over-expression is significantly associated with colorectal liver metastasis and is an independent predictor of poor survival for patients with colorectal cancer, indicating that CLMAT3 may act as an oncogene [1].

Disease

  • colorectal cancer [1]

Labs working on this lncRNA

  • Department of Oncological Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.[1]
  • Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200000, People's Republic of China.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Ye, L.C., et al., Aberrant expression of long noncoding RNAs in colorectal cancer with liver metastasis. Tumour Biol, 2015. 36(11): p. 8747-54.

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[XOK7EtLvnXsAfmUIVvs89QAAAAI] 2019-05-20 14:35:01: Fatal exception of type "TypeError"

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