Disease: non-small cell lung cancer (PMID:27409677)
Dysfunction type: regulation
Description: LncRNA BC087858 could promote cells invasion and induce non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT via up- regulating ZEB1 and Snail in NSCLC.
Function Mechanism: NA (PMID:27409677)
Biological Process: pathogenic process